N-Sulfinyl-p-anisidine

Base Information

• Chemical Name: N-Sulfinyl-p-anisidine
• CAS No.: 13165-69-0
• Molecular Formula: C7H7 N O2 S
• Molecular Weight: 169.204
• NSC Number: 75115
• DSSTox Substance ID: DTXSID00927309
• Nikkaji Number: J102.294F
• Wikidata: Q82901933
• Mol file: 13165-69-0.mol

Synonyms:1-methoxy-4-(sulfinylamino)benzene;N-Sulfinyl-p-anisidine;13165-69-0;4-Methoxy-N-sulfinylaniline;p-Methoxy-N-sulfinylaniline;p-Anisidine, N-sulfinyl-;N-Sulfinyl-p-methoxyaniline;Benzenamine, 4-methoxy-N-sulfinyl-;NSC75115;4-Methoxy-N-thionylaniline;Oprea1_393900;4-Methoxy-N-sulfinylaniline #;SCHEMBL3587840;DTXSID00927309;HFPOUXUCWPUERC-UHFFFAOYSA-N;MFCD00054491;NSC-75115;AKOS017259045;LS-09057;4-METHOXY-N-(OXO-??-SULFANYLIDENE)ANILINE;1-Methoxy-4-[(oxo-lambda~4~-sulfanylidene)amino]benzene;InChI=1/C7H7NO2S/c1-10-7-4-2-6(3-5-7)8-11-9/h2-5H,1H

Chemical Property of N-Sulfinyl-p-anisidine

Chemical Property:

• Vapor Pressure: 0.0195mmHg at 25°C
• Boiling Point: 260.8°Cat760mmHg
• Flash Point: 111.5°C
• PSA: 70.75000
• Density: 1.21g/cm³
• LogP: 2.58900
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 169.01974964
• Heavy Atom Count: 11
• Complexity: 160

Purity/Quality:

99% ^*data from raw suppliers

1-Methoxy-4-(sulfinylamino)benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)N=S=O

Technology Process of N-Sulfinyl-p-anisidine

There total 3 articles about N-Sulfinyl-p-anisidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

N-(chlorosulfinyl)imidazole (76541-52-1) + 4-methoxy-aniline (104-94-9) → p-methoxy-N-sulfinylaniline (13165-69-0)

Guidance literature:

In dichloromethane; 1.) -40 deg C, 2.) 20 deg C, 0.5 h;

DOI:10.1016/S0040-4039(00)89260-6

Reference yield: 75.0%

4-methoxy-aniline (104-94-9) → p-methoxy-N-sulfinylaniline (13165-69-0)

Guidance literature:

With hydrogenchloride; thionyl chloride; In benzene; Heating;

Reference yield:

→ p-methoxy-N-sulfinylaniline (13165-69-0)

Guidance literature:

DOI:10.1039/j29700000873 DOI:10.1016/S0040-4039(01)92865-5 DOI:10.1246/bcsj.39.1778

upstream raw materials:

4-methoxy-aniline

N-(chlorosulfinyl)imidazole

Downstream raw materials:

bis-(4-methoxy-phenyl)-diazene N-sulfide

4-(4-chloro-phenyl)-3-(4-methoxy-phenyl)-3H-[1,2,3,5]oxathiadiazole 2-oxide

3-(4-methoxy-phenyl)-2-oxo-5,6-diphenyl-2,3-dihydro-2λ⁴-[1,2,3]oxathiazin-4-one

3-(4-methoxy-phenyl)-4-phenyl-3H-[1,2,3,5]oxathiadiazole 2-oxide