Cyclopentanecarboxylic acid, 2-[[[(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropyl]amino]carbonyl]-4- [(7-methoxy-2-phenyl-4-quinolinyl)oxy]-, 1-(5-hexen-1-yl)-2,2-dimethylhydrazide, (1R,2R,4R)-

Base Information

Chemical Name:Cyclopentanecarboxylic acid, 2-[[[(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropyl]amino]carbonyl]-4- [(7-methoxy-2-phenyl-4-quinolinyl)oxy]-, 1-(5-hexen-1-yl)-2,2-dimethylhydrazide, (1R,2R,4R)-
CAS No.:924289-31-6
Molecular Formula:C39H48N4O6
Molecular Weight:668.833
Hs Code.:

Cyclopentanecarboxylic acid,
2-[[[(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropyl]amino]carbonyl]-4-
[(7-methoxy-2-phenyl-4-quinolinyl)oxy]-,
1-(5-hexen-1-yl)-2,2-dimethylhydrazide, (1R,2R,4R)-

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Chemical Property of Cyclopentanecarboxylic acid, 2-[[[(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropyl]amino]carbonyl]-4- [(7-methoxy-2-phenyl-4-quinolinyl)oxy]-, 1-(5-hexen-1-yl)-2,2-dimethylhydrazide, (1R,2R,4R)-

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Technology Process of Cyclopentanecarboxylic acid, 2-[[[(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropyl]amino]carbonyl]-4- [(7-methoxy-2-phenyl-4-quinolinyl)oxy]-, 1-(5-hexen-1-yl)-2,2-dimethylhydrazide, (1R,2R,4R)-

There total 1 articles about Cyclopentanecarboxylic acid, 2-[[[(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropyl]amino]carbonyl]-4- [(7-methoxy-2-phenyl-4-quinolinyl)oxy]-, 1-(5-hexen-1-yl)-2,2-dimethylhydrazide, (1R,2R,4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 862174-63-8
(1R,2R,4S)-2-((1R,2S)-1-ethoxycarbonyl-2-vinyl-cyclopropylcarbamoyl)-4-(7-methoxy-2-phenyl-quinolin-4-yloxy)-cyclopenteanecarboxylic acid tert-butyl ester

: 924289-30-5
2-(hex-5-en-1-yl)-1,1-dimethylhydrazine

: 924289-31-6
1-{[2-(N-hex-5-enyl-N,N'-dimethylhydrazinocarbonyl)-4-(7-methoxy-2-phenyl-quinolin-4-yloxy)-cyclopentanecarbonyl]-amino}-2-vinyl-cyclopropanecarboxylic acid ethyl ester

Guidance literature:: (1R,2R,4S)-2-((1R,2S)-1-ethoxycarbonyl-2-vinyl-cyclopropylcarbamoyl)-4-(7-methoxy-2-phenyl-quinolin-4-yloxy)-cyclopenteanecarboxylic acid tert-butyl ester; 2-(hex-5-en-1-yl)-1,1-dimethylhydrazine; With triethylsilane; trifluoroacetic acid; In dichloromethane; for 2h;

2-(hex-5-en-1-yl)-1,1-dimethylhydrazine; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 16.5h;

Reference yield: 71.0%

: 924289-31-6
1-{[2-(N-hex-5-enyl-N,N'-dimethylhydrazinocarbonyl)-4-(7-methoxy-2-phenyl-quinolin-4-yloxy)-cyclopentanecarbonyl]-amino}-2-vinyl-cyclopropanecarboxylic acid ethyl ester

: 13-dimethylamino-17-(7-methoxy-2-phenyl-quinolin-4-yloxy)-2,14-dioxo-3,13-diaza-tricyclo[13.3.0.0(4,6)]octadec-7-ene-4-carboxylic acid ethyl ester

Guidance literature:: [1,3-bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(O-isopropoxyphenylmethylene)ruthenium; In dichloromethane; for 16h; Heating / reflux;