N6-Carbamoyl-L-threonyladenosine

Base Information

Chemical Name:N6-Carbamoyl-L-threonyladenosine
CAS No.:24719-82-2
Molecular Formula:C15H20 N6 O8
Molecular Weight:412.359
Hs Code.:
UNII:3C55P4W4TB
DSSTox Substance ID:DTXSID70947655
Nikkaji Number:J39.573K
Wikidata:Q15632802
Metabolomics Workbench ID:49460
Mol file:24719-82-2.mol

Synonyms:N(6)-(N-threonylcarbonyl)adenosine;N(6)-(N-threonylcarbonyl)adenosine, (D)-isomer;N-((9-beta-D-ribofuranosylpurin-6-yl)-carbamoyl)threonine;N-(9-(beta-D-ribofuranosyl)purin-6-ylcarbamoyl)threonine;N-(purin-6-ylcarbamoyl)-L-threonine riboside;N6-threonylcarbamoyladenosine;t(6)a

Suppliers and Price of N6-Carbamoyl-L-threonyladenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N6-(N-Threonylcarbonyl)adenosine
10mg
$ 305.00

Biosynth Carbosynth
N6-Carbamoylthreonyladenosine sodium salt
25 mg
$ 1444.00

Biosynth Carbosynth
N6-Carbamoylthreonyladenosine sodium salt
10 mg
$ 630.00

Biosynth Carbosynth
N6-Carbamoylthreonyladenosine sodium salt
5 mg
$ 367.50

Biosynth Carbosynth
N6-Carbamoylthreonyladenosine sodium salt
2 mg
$ 190.00

Biosynth Carbosynth
N6-Carbamoylthreonyladenosine sodium salt
1 mg
$ 105.00

Total 21 raw suppliers

Chemical Property of N6-Carbamoyl-L-threonyladenosine

Chemical Property:

Melting Point:>156°C (dec.)
Boiling Point:°Cat760mmHg
PKA:1.99±0.10(Predicted)
Flash Point:°C
PSA：215.01000
Density:1.96g/cm³
LogP:-3.47750
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly)
XLogP3:-2.6
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:6
Exact Mass:412.13426162
Heavy Atom Count:29
Complexity:613

Purity/Quality:

99% ^*data from raw suppliers

N6-(N-Threonylcarbonyl)adenosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C(=O)O)NC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O)O
Isomeric SMILES:C[C@H]([C@@H](C(=O)O)NC(=O)NC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)O
Uses N6-(N-Threonylcarbonyl)adenosine is an essential modified nucleoside found in tRNA responsible for ANN codons in all three domains of life. It is also a biological marker in neoplastic diseases.

Technology Process of N6-Carbamoyl-L-threonyladenosine

There total 12 articles about N6-Carbamoyl-L-threonyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 56893-27-7
2-(3-(9-((2R,3R,4R,5R)-3,4-diacetoxy-5-(acetoxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)ureido)-3-hydroxybutanoic acid

: 24719-82-2
N⁶-threonylcarbamoyladenosine

Guidance literature:: With ammonia; In methanol; at 20 - 40 ℃;
DOI:10.1002/anie.201801919

Reference yield:

: C₁₅H₁₉N₆O₈^(1-)*C₁₆H₃₆N⁽¹⁺⁾

: 24719-82-2
N⁶-threonylcarbamoyladenosine

Guidance literature:: With calcium carbonate; In methanol; at 20 ℃; for 1h;
DOI:10.1039/d0ra09803e

Reference yield:

: 7387-57-7,953089-09-3
triacetyladenosine

: 24719-82-2
N⁶-threonylcarbamoyladenosine

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia; hydrogen cation / methanol

2: hydrogen cation

With ammonia; hydrogen cation; In methanol;
DOI:10.1093/nar/gkw1189