Methyl isocyanide

Base Information

Chemical Name:Methyl isocyanide
CAS No.:593-75-9
Molecular Formula:C₂H₃N
Molecular Weight:41.0525
Hs Code.:
European Community (EC) Number:209-806-9
UNII:B5B6DXM7GG
DSSTox Substance ID:DTXSID3075040
Nikkaji Number:J2.698K
Wikipedia:Methyl_isocyanide
Wikidata:Q2435355
Metabolomics Workbench ID:52365
Mol file:593-75-9.mol

Synonyms:methyl isocyanide;methylisonitrile

Suppliers and Price of Methyl isocyanide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL ISOCYANIDE 98.00%
5MG
$ 503.80

Total 40 raw suppliers

Chemical Property of Methyl isocyanide

Chemical Property:

Melting Point:-45°C
Refractive Index:1.3427
Boiling Point:81.65°C (estimate)
PSA：0.00000
Density:0.7424
LogP:-0.23380
Storage Temp.:Refrigerator, Under inert atmosphere
Solubility.:Chloroform (Soluble), Methanol (Slightly)
Water Solubility.:91g/L(15 oC)
XLogP3:0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:41.026549100
Heavy Atom Count:3
Complexity:29.3

Purity/Quality:

99%, ^*data from raw suppliers

METHYL ISOCYANIDE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[N+]#[C-]
Recent ClinicalTrials:Safety and Immunogenicity Evaluation After One or Two Doses of Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Infants and Toddlers
Uses Isocyanomethane can be used as porous embolization microspheres comprising drugs.

Technology Process of Methyl isocyanide

There total 56 articles about Methyl isocyanide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 4381-85-5
2,5-diaza-3,4-dimethyl-2,4-hexadiene

: 79-16-3
N-methyl-acetamide

: 593-75-9,685498-28-6
methyl isocyanate

Guidance literature:: With oxygen; rose bengal; In acetonitrile; at 13 ℃; for 9h; Irradiation;
DOI:10.1021/jo00027a041

Reference yield: 87.0%

: Ni2(μ-CNMe)(CNMe)2(dppm)2

: 1197040-29-1,931-54-4
phenyl isocyanate

: Ni2(μ-CNC6H5)(CNMe)2(bis(diphenylphosphino)methane)2

: 593-75-9,685498-28-6
methyl isocyanate

Guidance literature:: In benzene; under N2; evapn. under vac., residue redissolved in benzene, addn. of hexane, filtered out, rinsed with acetonitrile and ether, dried under vac., recrystn. (benzene/hexane);

Reference yield: 84.0%

: {Ni3(μ3-η1-methylisocyanide)(μ3-I)(methylisocyanide)2(dppm)2}I

: 2071-20-7
bis-diphenylphosphinomethane

: 593-75-9,685498-28-6
methyl isocyanate

: {Ni₃(CNCH₃)I(P(C₆H₅)2CH₂P(C₆H₅)2)3}⁽¹⁺⁾*I^(1-)*CH₂Cl₂={Ni₃(CNCH₃)I(P(C₆H₅)2CH₂P(C₆H₅)2)3}I*CH₂Cl₂

Guidance literature:: In acetonitrile; addn. of the ligand (dppm) to a stirred soln. of the complex at room temp., refluxing, 36 h, with occasional purging with N2 (to remouve the volatile CNMe); vac. evapn., residue recrystn. (CH2Cl2-pentane), washed (CH3CN and Et2O), vac. dried;
DOI:10.1016/S0277-5387(00)86755-8