2-[[(6-Chloro-3-pyridinyl)Methyl]aMino]cyclopentanecarbonitrile

Base Information

Chemical Name:2-[[(6-Chloro-3-pyridinyl)Methyl]aMino]cyclopentanecarbonitrile
CAS No.:924669-64-7
Molecular Formula:C₁₂H₁₄ClN₃
Molecular Weight:235.716
Hs Code.:
Mol file:924669-64-7.mol

Synonyms:2-[[(6-Chloro-3-pyridinyl)methyl]amino]cyclopentanecarbonitrile;

Suppliers and Price of 2-[[(6-Chloro-3-pyridinyl)Methyl]aMino]cyclopentanecarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[[(6-Chloro-3-pyridinyl)methyl]amino]cyclopentanecarbonitrile
50mg
$ 165.00

Total 1 raw suppliers

Chemical Property of 2-[[(6-Chloro-3-pyridinyl)Methyl]aMino]cyclopentanecarbonitrile

Chemical Property:

Boiling Point:414.7±45.0 °C (760 mmHg)
PKA:6.99±0.40(Predicted)
PSA：48.71000
Density:1.22±0.1 g/cm3 (20 °C, 760 mmHg)
LogP:2.90778

Purity/Quality:: 2-[[(6-Chloro-3-pyridinyl)methyl]amino]cyclopentanecarbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-[[(6-Chloro-3-pyridinyl)methyl]amino]cyclopentanecarbonitrile is an octahydro-1H-cyclopenta[d]pyrimidine derivative with potential insecticidal activities against Aphis craccivora.

Technology Process of 2-[[(6-Chloro-3-pyridinyl)Methyl]aMino]cyclopentanecarbonitrile

There total 3 articles about 2-[[(6-Chloro-3-pyridinyl)Methyl]aMino]cyclopentanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 70258-18-3
2-chloro-5-(chloromethyl)pyridine

: 80501-45-7,874294-11-8,874293-75-1
2-amino-cyclopentanecarbonitrile

: 924669-64-7
2-((6-chloropyridin-3-yl)methylamino)cyclopentanecarbonitrile

Guidance literature:: With triethylamine; In acetonitrile; at 50 - 55 ℃; for 15h;
DOI:10.1021/jf062845l

Reference yield:

: 111-69-3
hexanedinitrile

: 924669-64-7
2-((6-chloropyridin-3-yl)methylamino)cyclopentanecarbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / NaH / tetrahydrofuran

2: 65 percent / NaHB(OAc)3; acetic acid / 3 h / 20 °C

3: 63 percent / Et₃N / acetonitrile / 15 h / 50 - 55 °C

With sodium tris(acetoxy)borohydride; sodium hydride; acetic acid; triethylamine; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jf062845l

Reference yield:

: 2321-76-8
2-iminocyclopentanecarbonitrile

: 924669-64-7
2-((6-chloropyridin-3-yl)methylamino)cyclopentanecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / NaHB(OAc)3; acetic acid / 3 h / 20 °C

2: 63 percent / Et₃N / acetonitrile / 15 h / 50 - 55 °C

With sodium tris(acetoxy)borohydride; acetic acid; triethylamine; In acetonitrile;
DOI:10.1021/jf062845l