N-(2-Methylphenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-acetamide

Base Information

Chemical Name:N-(2-Methylphenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-acetamide
CAS No.:134616-45-8
Molecular Formula:C₁₇H₁₆N₂O₂S
Molecular Weight:312.392
Hs Code.:
DSSTox Substance ID:DTXSID90928688

Synonyms:BRN 4819335;2-[4-(2-methylphenyl)-3-oxo-1,4-benzothiazin-2-yl]acetamide;N-(2-Methylphenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-acetamide;2H-1,4-Benzothiazine-2-acetamide, 3,4-dihydro-N-(2-methylphenyl)-3-oxo-;DTXSID90928688;LS-40528;2-[4-(2-Methylphenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]ethanimidic acid

Suppliers and Price of N-(2-Methylphenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-(2-Methylphenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-acetamide

Chemical Property:

Vapor Pressure:3.41E-16mmHg at 25°C
Boiling Point:638.4°Cat760mmHg
Flash Point:339.9°C
PSA：89.69000
Density:1.29g/cm³
LogP:4.22410
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:312.09324893
Heavy Atom Count:22
Complexity:442

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1N2C3=CC=CC=C3SC(C2=O)CC(=O)N

Technology Process of N-(2-Methylphenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-acetamide

There total 6 articles about N-(2-Methylphenyl)-3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 80167-54-0
(E)-3-o-Tolylcarbamoyl-acrylic acid methyl ester

: 137-07-5
2-amino-benzenethiol

: 134616-45-8
2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-o-tolyl-acetamide

Guidance literature:: In N,N-dimethyl-formamide; Heating;

Reference yield: 54.0%

: 134616-44-7
2(H)-oxo-3,3a-dihydrofuro<3,2-b><1,4> benzothiazine

: 95-53-4
o-toluidine

: 134616-45-8
2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-o-tolyl-acetamide

Guidance literature:: With acetic acid; In benzene; for 4h; Heating;

Reference yield:

: 53616-19-6
(2-methylphenyl)maleamic acid

: 134616-45-8
2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-o-tolyl-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 49 percent / phosphorus pentoxide / Heating

2: 59 percent / aniline / ethanol / Heating

3: 70 percent / dimethylformamide / Heating

With phosphorus pentaoxide; aniline; In ethanol; N,N-dimethyl-formamide;