6-(2-NITRO-PHENYL)-IMIDAZO[2,1-B]THIAZOLE-3-CARBOXYLIC ACID ETHYL ESTER

Base Information

• Chemical Name: 6-(2-NITRO-PHENYL)-IMIDAZO[2,1-B]THIAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
• CAS No.: 925437-84-9
• Molecular Formula: C14H11N3O4S
• Molecular Weight: 317.325
• Hs Code.: 2934100090
• Mol file: 925437-84-9.mol

Synonyms:ethyl 6-(2-nitrophenyl)imidazo[2,1-b][1,3]thiazole-3-carboxylate;

Chemical Property of 6-(2-NITRO-PHENYL)-IMIDAZO[2,1-B]THIAZOLE-3-CARBOXYLIC ACID ETHYL ESTER

Chemical Property:

• PSA: 117.66000
• LogP: 3.67090
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 6-(2-nitrophenyl)imidazo-[2,1-b]thiazole-3-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-(2-NITRO-PHENYL)-IMIDAZO[2,1-B]THIAZOLE-3-CARBOXYLIC ACID ETHYL ESTER

There total 1 articles about 6-(2-NITRO-PHENYL)-IMIDAZO[2,1-B]THIAZOLE-3-CARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-aminothiazole-4-carboxylate (5398-36-7) + 2-bromo-1-(2-nitrophenyl)ethanone (6851-99-6) → 6-(2-nitrophenyl)-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester (925437-84-9)

Guidance literature:

In butanone; for 18h; Reflux;

DOI:10.1021/jm8012954

Reference yield: 74.0%

6-(2-nitrophenyl)-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester (925437-84-9) + isobutyl chloroformate (543-27-1) → (6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl)methanol (925437-85-0)

Guidance literature:

With 4-methyl-morpholine; sodium hydroxide; sodium tetrahydroborate; In tetrahydrofuran; water; ethyl acetate; pentane;

Reference yield: 74.0%

6-(2-nitrophenyl)-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester (925437-84-9) → (6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl)methanol (925437-85-0)

Guidance literature:

6-(2-nitrophenyl)-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester; With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 18h;

With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at 0 ℃; for 3h;

With sodium tetrahydroborate; water; In tetrahydrofuran; at 0 ℃; for 0.75h;

DOI:10.1016/bs.mie.2016.01.012

upstream raw materials:

2-aminothiazole-4-carboxylate

2-bromo-1-(2-nitrophenyl)ethanone

Downstream raw materials:

6-(2-nitro-phenyl)-imidazo[2,1-b]thiazole-3-carboxylic acid

(6-(2-nitrophenyl)imidazo[2,1-b]thiazol-3-yl)methanol

4-[6-(2-aminophenyl)imidazo[2,1-b]thiazol-3-ylmethyl]piperazine-1-carboxylic acid tert-butyl ester

C₃₀H₃₁N₇O₃S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 925437-84-9 6-(2-NITRO-PHENYL)-IMIDAZO[2,1-B]THIAZOLE-3-CARBOXYLIC ACID ETHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send