Encainide

Base Information

Chemical Name:Encainide
CAS No.:66778-36-7
Deprecated CAS:37612-13-8
Molecular Formula:C₂₂H₂₈N₂O₂
Molecular Weight:352.477
Hs Code.:
UNII:SY3J0147NB
DSSTox Substance ID:DTXSID0022983
Nikkaji Number:J1.621.570H
Wikipedia:Encainide
Wikidata:Q514534
NCI Thesaurus Code:C65511
Metabolomics Workbench ID:43440
ChEMBL ID:CHEMBL315838

Synonyms:Encainide;Encainide Hydrochloride;Encainide Hydrochloride, (+-)-Isomer;Encainide, (+)-Isomer;Encainide, (-)-Isomer;Enkaid;MJ 9067;MJ-9067;MJ9067

Suppliers and Price of Encainide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Methoxy-N-(2-(2-(1-methylpiperidin-2-yl)ethyl)phenyl)benzamide 95+%
1g
$ 1488.00

American Custom Chemicals Corporation
ENCAINIDE 95.00%
1G
$ 2355.15

American Custom Chemicals Corporation
ENCAINIDE 95.00%
100MG
$ 885.31

Total 13 raw suppliers

Chemical Property of Encainide

Chemical Property:

Melting Point:128 - 131 °C (acetonitrile)
PSA：41.57000
LogP:4.37530
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:352.215078140
Heavy Atom Count:26
Complexity:434

Purity/Quality:

97% ^*data from raw suppliers

4-Methoxy-N-(2-(2-(1-methylpiperidin-2-yl)ethyl)phenyl)benzamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC
Recent ClinicalTrials:Cardiac Arrhythmia Suppression Trial (CAST)

Technology Process of Encainide

There total 11 articles about Encainide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 4-methoxy-N-(2-vinylphenyl)benzamide

: 7730-87-2,35677-86-2,41447-17-0,41447-18-1
1-methylpiperidine-2-carboxylic acid

: 58754-48-6,58754-49-7,66778-36-7,37612-13-8
encainide

Guidance literature:: With [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; caesium carbonate; In dimethyl sulfoxide; at 45 ℃; for 24h; Inert atmosphere; Irradiation;
DOI:10.1021/acs.orglett.6b01712

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 87085-10-7,130021-70-4,130021-71-5,58754-40-8
N-Desmethylencainide

: 58754-48-6,58754-49-7,66778-36-7,37612-13-8
encainide

Guidance literature:: With hydrogen; palladium on activated charcoal; In acetic acid; at 23 ℃; for 16h; under 760 Torr;
DOI:10.1002/jhet.5570300321

Reference yield:

: 153707-65-4
N-{2-[1-Hydroxy-2-(1-methyl-1,2,5,6-tetrahydro-pyridin-2-yl)-ethyl]-phenyl}-4-methoxy-benzamide

: 58754-48-6,58754-49-7,66778-36-7,37612-13-8
encainide

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; at 65 ℃; for 16h; Yield given;
DOI:10.1002/jhet.5570300321