3-(1,2-Dimethyl-3-indolyl)phthalide

Base Information

• Chemical Name: 3-(1,2-Dimethyl-3-indolyl)phthalide
• CAS No.: 73973-00-9
• Molecular Formula: C₁₈H₁₅NO₂
• Molecular Weight: 277.323
• DSSTox Substance ID: DTXSID70995217
• Nikkaji Number: J107.142D
• Mol file: 73973-00-9.mol

Synonyms:73973-00-9;3-(1,2-Dimethyl-3-indolyl)phthalide;BRN 0891179;Phthalide, 3-(1,2-dimethyl-3-indolyl)-;3-(1,2-Dimethyl-1H-indol-3-yl)isobenzofuran-1(3H)-one;starbld0013055;SCHEMBL9848542;DTXSID70995217;AKOS040767534;3-(1,2-Dimethyl-1H-indol-3-yl)phthalide;LS-109399;3-(1,2-dimethylindol-3-yl)-3H-isobenzofuran-1-one;3-(1,2-Dimethyl-1H-indol-3-yl)-2-benzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 3-(1,2-dimethyl-1H-indol-3-yl)-

Chemical Property of 3-(1,2-Dimethyl-3-indolyl)phthalide

Chemical Property:

• Vapor Pressure: 1.12E-09mmHg at 25°C
• Melting Point: 204-206 °C(Solv: benzene (71-43-2))
• Boiling Point: 488.1°Cat760mmHg
• Flash Point: 249°C
• PSA: 31.23000
• Density: 1.25g/cm³
• LogP: 3.74650
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 277.110278721
• Heavy Atom Count: 21
• Complexity: 423

Purity/Quality:

99% ^*data from raw suppliers

3-(1,2-DIMETHYL-3-INDOLYL)PHTHALIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C2=CC=CC=C2N1C)C3C4=CC=CC=C4C(=O)O3

Technology Process of 3-(1,2-Dimethyl-3-indolyl)phthalide

There total 2 articles about 3-(1,2-Dimethyl-3-indolyl)phthalide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dimethylindole (875-79-6) + o-carboxybenzaldehyde (119-67-5) → 1,2-Dimethyl-3-phthalidyl-indol (73973-00-9)

Guidance literature:

In benzene; for 2h; Heating;

DOI:10.1039/jr9650000680

Reference yield:

→ 1,2-Dimethyl-3-phthalidyl-indol (73973-00-9)

Guidance literature:

1,2-Dimethyl-indol, Phthalaldehydsaeure, 200-220grad, (kurz 270grad), Ausb. 100percent;

DOI:10.1021/ja01504a031

upstream raw materials:

1,2-dimethylindole

o-carboxybenzaldehyde