875-79-6

Basic information

• Product Name: 1,2-Dimethylindole
• Synonyms: 1,2-DIMETHYLINDOLE;1,2-Dimethyl-1H-indole;Indole, 1,2-dimethyl-;N-Methyl-2-methylindole;Dimethylindole;NSC 62087;1,2-Dimethylindole 99%
• CAS NO: 875-79-6
• Molecular Formula: C₁₀H₁₁N
• Molecular Weight: 145.2
• EINECS: 212-877-9
• Product Categories: Intermediates of Dyes and Pigments;Indole;Indoles;Simple Indoles;Building Blocks;Heterocyclic Building Blocks;Heterocycle-Indole series
• Mol File: 875-79-6.mol
• Article Data: 91

Chemical Properties

• Melting Point: 55-58 °C(lit.)
• Boiling Point: 143 °C / 30mmHg
• Flash Point: >230 °F
• Appearance: /Liquid
• Density: 0.99 g/cm³
• Vapor Pressure: 0.0198mmHg at 25°C
• Refractive Index: 1.561
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Stability: Stable, but light sensitive. Incompatible with strong oxidizing agents.
• CAS DataBase Reference: 1,2-Dimethylindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Dimethylindole(875-79-6)
• EPA Substance Registry System: 1,2-Dimethylindole(875-79-6)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 875-79-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 875-79-6 differently. You can refer to the following data:
1. Building block for preparation of 3-functionalized indoles Building block for preparation carbazoles Building block for preparation of cyanoindoles Reactant for preparation of trifluoromethylindoles Reactant for preparation of potent antihyperlipidemic agents Building block in iso-Nazarov or Nazarov cyclizations Reactant for preparation of GSK-3 inhibitors Building block for preparation of carboxyindoles Reactant for preparation of plant growth promoters Reactant for preparation of tryptophan derivatives.
2. Building block for preparation of 3-functionalized indolesBuilding block for preparation carbazolesBuilding block for preparation of cyanoindolesReactant for preparation of trifluoromethylindolesReactant for preparation of potent antihyperlipidemic agentsBuilding block in iso-Nazarov or Nazarov cyclizationsReactant for preparation of GSK-3? inhibitorsBuilding block for preparation of carboxyindolesReactant for preparation of plant growth promotersReactant for preparation of tryptophan derivatives

InChI:InChI=1/C10H11N/c1-8-7-9-5-3-4-6-10(9)11(8)2/h3-7H,1-2H3

Upstream product

• 69887-86-1 1,2-dimethyl-3-nitro-pyridinium 
• 6407-34-7 methyl-1 ethylideneamine 
• 95-20-5 2-methyl-1H-indole 
• 74-88-4 methyl iodide 
• 100-61-8 N-methylaniline 
• 1485-23-0 2-(N-methyl)indolylmethyl acetate 
• 124-38-9 carbon dioxide 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 37493-34-8 methyl 1-methyl-1H-indole-2-carboxylate 
• 78307-58-1 1-(2-Methylamino-phenyl)-propan-2-one 
• 26216-93-3 1,2-dimethylindoline 
• 6628-07-5 N-allyl-N-methylaniline 
• 31399-19-6 1-(ethyl(phenyl)amino)propan-2-one 
• 4348-19-0 N-ethylaniline hydrochloride 

Downstream Products

• 73973-00-9 1,2-Dimethyl-3-phthalidyl-indol 
• 33022-90-1 1-(1,2-dimethyl-1H-indol-3-yl)ethanone 
• 75528-45-9 3-(1,2-Dimethyl-3-indolyl)-1-phenylpropan-1-on 
• 87401-40-9 1,2-dimethyl-octahydro-indole 
• 110051-43-9 2-(1,2-dimethyl-indol-3-yl)-1-methyl-2-phenyl-ethylamine 
• 87926-14-5 2-propyl-N-methyl-aniline 
• 114792-64-2 N-[2-(1,2-dimethyl-indol-3-yl)-1-methyl-2-phenyl-ethyl]-phthalimide 
• 64232-30-0 2,4-bis-(1,2-dimethyl-indol-3-yl)-4-oxo-butyric acid 
• 21528-33-6 3-{p-di(n-butyl)aminophenyl}-3-(1',2'-dimethylindole-3'-yl)phthalide 
• 877383-20-5 C₃₁H₂₇N₃O₂ 
• 1184923-69-0 3,3'-((2-(4-methoxyphenoxy)phenyl)methylene)bis(1,2-dimethyl-1H-indole) 
• 108240-32-0 1,2-dimethyl-3-(2-nitro-1-phenyl-ethyl)-indole 
• 1312707-16-6 C₁₇H₁₈N₂ 
• 1380108-65-5 C₂₉H₃₆N₂ 

Relevant articles and documents

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Asymmetric transfer hydrogenation of heterocycle-containing acetophenone derivatives using N-functionalised [(benzene)Ru(II)(TsDPEN)] complexes

The application of enantiomerically-pure ruthenium(II) catalysts containing N - functionalised TsDPEN ligand to the asymmetric transfer hydrogenation of 15 examples of α-heterocyclic acetophenone derivatives is reported. Products of up to 99% ee were formed.

Synthesis of 3-halogenated 2,3′-biindoles by a copper-mediated 2,3-difunctionalization of indoles

A copper-mediated 2,3-difunctionalization of indoles to afford 3-halogenated 2,3′-biindoles is described herein. The protocol uses readily available feedstocks and a naturally abundant copper catalyst system, which allows the regioselective formation of C-C and C-X (X = Cl & Br) bonds in one single operation. Here the copper metal salt serves not only as a catalyst but also as a reactant to provide the source of halogen. This operationally simple procedure avoids the utilization of environmentally unfriendly reagents and displays good functional group compatibility. Noteworthily, the introduction of halogen into molecules would offer great potential for further chemical transformations. This journal is

Facile C-S Bond Cleavage of Aryl Sulfoxides Promoted by Bronsted Acid

A method for the Bronsted acid promoted desulfination of aryl sulfoxides is presented. In the presence of a thiol, electron-rich sulfoxides undergo C-S bond cleavage to give the corresponding protodesulfinated arenes and disulfides.