Technology Process of Phenylalaninamide,
N-(1-naphthalenylsulfonyl)glycyl-4-(aminothioxomethyl)-N-butyl-
There total 6 articles about Phenylalaninamide,
N-(1-naphthalenylsulfonyl)glycyl-4-(aminothioxomethyl)-N-butyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
TEA; hydrogen sulfide;
In
pyridine;
for 72h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: NaOH (1 mol/l) / acetic acid; H2O / pH 3.8-4.0
2: NaOH (1 mol/l) / diethyl ether; ethyl acetate; H2O / 10 h
3: DCC / pyridine / 12 h / Ambient temperature
4: 55 percent / pyridine; dimethylformamide / 7 h / Ambient temperature
5: 85 percent / H2S, TEA / pyridine / 72 h / Ambient temperature
With
sodium hydroxide; TEA; hydrogen sulfide; dicyclohexyl-carbodiimide;
In
pyridine; diethyl ether; water; acetic acid; ethyl acetate; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: SOCl2 / 1 h / Heating
2: NaOH (1 mol/l) / diethyl ether; ethyl acetate; H2O / 10 h
3: DCC / pyridine / 12 h / Ambient temperature
4: 55 percent / pyridine; dimethylformamide / 7 h / Ambient temperature
5: 85 percent / H2S, TEA / pyridine / 72 h / Ambient temperature
With
sodium hydroxide; thionyl chloride; TEA; hydrogen sulfide; dicyclohexyl-carbodiimide;
In
pyridine; diethyl ether; water; ethyl acetate; N,N-dimethyl-formamide;
![N-Butyl-3-(4-cyano-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionamide](/Databaselist/images/loading.webp)
