1-Benzyl-1H-pyrrole-3,4-dicarbaldehyde

Base Information

• Chemical Name: 1-Benzyl-1H-pyrrole-3,4-dicarbaldehyde
• CAS No.: 92763-72-9
• Molecular Formula: C13H11NO2
• Molecular Weight: 213.236
• DSSTox Substance ID: DTXSID00535423
• Wikidata: Q82409723

Synonyms:1-Benzyl-1H-pyrrole-3,4-dicarbaldehyde;92763-72-9;DTXSID00535423

Chemical Property of 1-Benzyl-1H-pyrrole-3,4-dicarbaldehyde

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 213.078978594
• Heavy Atom Count: 16
• Complexity: 232

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CN2C=C(C(=C2)C=O)C=O

Technology Process of 1-Benzyl-1H-pyrrole-3,4-dicarbaldehyde

There total 5 articles about 1-Benzyl-1H-pyrrole-3,4-dicarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

1-benzyl-1H-pyrrole-3,4-dicarbonitrile (927203-48-3) → 1-benzyl-1H-pyrrole-3,4-dicarbaldehyde (92763-72-9)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; at -50 ℃; for 4h;

DOI:10.1021/ja0658259

Reference yield:

benzyl bromide (100-39-0) → 1-benzyl-1H-pyrrole-3,4-dicarbaldehyde (92763-72-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 2 h / 0 °C

1.2: 79 percent / tetrahydrofuran; dimethylformamide / 10 h / 20 °C

2.1: 55 percent / DIBAL / CH₂Cl₂ / 4 h / -50 °C

With sodium hydride; diisobutylaluminium hydride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja0658259

Reference yield:

(1-Benzyl-4-hydroxymethyl-1H-pyrrol-3-yl)-methanol (92763-89-8) → 1-benzyl-1H-pyrrole-3,4-dicarbaldehyde (92763-72-9)

Guidance literature:

With barium permanganate;

upstream raw materials:

(1-Benzyl-4-hydroxymethyl-1H-pyrrol-3-yl)-methanol

1-benzyl-1H-pyrrole-3,4-dicarbonitrile

benzyl bromide

1-Benzyl-1H-pyrrol-3,4-dicarbonsaeuredimethylester

Downstream raw materials:

2-Benzyl-6,7-dihydro-2H-benzo[f]isoindole-5,8-dione

2,8-Dibenzyl-2H,8H-2,8-diaza-dicyclopenta[b,i]anthracene-5,11-dione

2-benzyl-2H-pyrrolo[3,4-c]pyridine-6-carboxylic acid ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 92763-72-9 1H-Pyrrole-3,4-dicarboxaldehyde, 1-(phenylmethyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send