(2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one

Base Information

• Chemical Name: (2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one
• CAS No.: 16240-00-9
• Molecular Formula: C17H16 N2 O S
• Molecular Weight: 296.393
• Mol file: 16240-00-9.mol

Synonyms:4-Thiazolidinone,3-o-tolyl-2-(o-tolylimino)- (8CI); NSC 375281

Chemical Property of (2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one

Chemical Property:

• Vapor Pressure: 4.34E-08mmHg at 25°C
• Boiling Point: 444.3°Cat760mmHg
• Flash Point: 222.5°C
• Density: 1.2g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one

There total 8 articles about (2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.4%

N,N'-di(o-tolyl)thiourea (137-97-3) + bromoacetic acid (79-08-3) → 2-(o-tolyl)imino-3-(o-tolyl)-thiazolidin-4-one (16240-00-9)

Guidance literature:

With sodium acetate; In ethanol; for 6h; Heating;

DOI:10.1021/jo0625554

Reference yield:

N,N-di-o-tolylthiourea (22695-18-7) + chloroacetic acid (79-11-8) → 2-(o-tolyl)imino-3-(o-tolyl)-thiazolidin-4-one (16240-00-9)

Guidance literature:

With ethanol;

Reference yield:

N,N'-di(o-tolyl)thiourea (137-97-3) + chloroacetic acid ethyl ester (105-39-5) → C17H16N2OS (16240-00-9)

Guidance literature:

With sodium acetate; In ethanol; at 60 ℃;

DOI:10.1039/c8cc07810f

upstream raw materials:

S-ethyl-N,N'-di-o-tolyl-isothiourea

mercaptoacetic acid

S-methyl-N,N'-di-o-tolyl-isothiourea

N,N-di-o-tolylthiourea

Downstream raw materials:

5-furfurylidene-3-o-tolyl-2-o-tolylimino-thiazolidin-4-one

5-(4-dimethylamino-benzylidene)-3-o-tolyl-2-o-tolylimino-thiazolidin-4-one

3-o-tolylthiazolidine-2,4-dione

N,N'-bis(2-methylphenyl)urea