1-(Furan-2-yl)but-3-en-1-ol

Base Information

• Chemical Name: 1-(Furan-2-yl)but-3-en-1-ol
• CAS No.: 6398-51-2
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.166
• European Community (EC) Number: 620-856-4
• NSC Number: 75454
• DSSTox Substance ID: DTXSID70982708
• Nikkaji Number: J47.861J
• Mol file: 6398-51-2.mol

Synonyms:1-(furan-2-yl)but-3-en-1-ol;6398-51-2;1-(2-furyl)-3-butene-1-ol;1-(2-Furyl)-3-buten-1-ol;4-(2-Furyl)-1-buten-4-ol;NSC75454;4-(2-FURYL)-1-BUTEN-4-OL 97;alpha-Allyl-2-furanmethanol;SCHEMBL817666;2-(1-hydroxy-3-butenyl)furan;2-(1-hydroxy-3-butenyl) furan;2-(1-hydroxy-3-butenyl)-furan;DTXSID70982708;1-(Furan-2-yl)-3-buten-1-ol;1-(furan-2-yl)-but-3-en-1-ol;MFCD03093935;NSC-75454;AKOS012009859;AT23581;SB60981;BS-51662;F1226

Chemical Property of 1-(Furan-2-yl)but-3-en-1-ol

Chemical Property:

• Vapor Pressure: 0.445mmHg at 25°C
• Refractive Index: n20/D 1.492(lit.)
• Boiling Point: 204-205 °C(lit.)
• PKA: 13.89±0.20(Predicted)
• Flash Point: 185 °F
• PSA: 33.37000
• Density: 1.06 g/mL at 25 °C(lit.)
• LogP: 1.88910
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 138.068079557
• Heavy Atom Count: 10
• Complexity: 112

Purity/Quality:

97% ^*data from raw suppliers

1-(Furan-2-yl)but-3-en-1-ol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCC(C1=CC=CO1)O

Technology Process of 1-(Furan-2-yl)but-3-en-1-ol

There total 38 articles about 1-(Furan-2-yl)but-3-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

furfural (98-01-1) + allylmagnesium bromide (2622-05-1) → 1-(furan-2-yl)but-3-en-1-ol (119619-39-5,119678-68-1,6398-51-2,144730-99-4)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 2h;

DOI:10.1002/chem.201301980

Reference yield: 97.0%

furfural (98-01-1) + allyl bromide (106-95-6) → 1-(furan-2-yl)but-3-en-1-ol (119619-39-5,119678-68-1,6398-51-2,144730-99-4)

Guidance literature:

With potassium fluoride; antimony; water; In methanol; at 25 - 30 ℃; for 2.5h; Sonication;

DOI:10.1080/00397910802654856

Reference yield: 96.0%

furfural (98-01-1) + allyltributylstanane (24850-33-7) → (S)-1-(2-furyl)-3-buten-1-ol (6398-51-2,119619-39-5,119678-68-1,144730-99-4)

Guidance literature:

bis(((S)-binaphthoxy)(isopropoxy)titanium) oxide; In dichloromethane; at 0 ℃; for 18h;

DOI:10.1002/chem.200305078

upstream raw materials:

furfural

allylmagnesium bromide

allyltributylstanane

C₁₅H₃₂BrSb

Downstream raw materials:

(R)-1-furan-2-yl-but-3-en-1-ol

(S)-1-(2-furyl)-3-buten-1-ol

(R)-(+)-1-(2-furyl)but-3-en-1-yl acetate

2,4-bis-ethoxymethoxy-6-methyl-benzoic acid 1-furan-2-yl-but-3-enyl ester