Acetylsolasodine

Base Information

Chemical Name:Acetylsolasodine
CAS No.:6159-99-5
Molecular Formula:C₂₉H₄₅NO₃
Molecular Weight:455.681
Hs Code.:
NSC Number:96021
DSSTox Substance ID:DTXSID60294382
ChEMBL ID:CHEMBL1390509

Synonyms:O-acetylsolasodine;spirosol-5-en-3-yl acetate

Suppliers and Price of Acetylsolasodine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Acetylsolasodine

Chemical Property:

Vapor Pressure:5.63E-12mmHg at 25°C
Boiling Point:546°Cat760mmHg
Flash Point:284°C
Density:1.12g/cm³
XLogP3:6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:455.33994430
Heavy Atom Count:33
Complexity:854

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC(=O)C)C)C)C)NC1

Technology Process of Acetylsolasodine

There total 11 articles about Acetylsolasodine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 5,6-epoxy-solasodine-3β-acteate

: 1415-78-7,6159-99-5
solasodine-3β-acetate

Guidance literature:: With iodine; triphenylphosphine; In dichloromethane; at 25 ℃; for 1h;
DOI:10.1016/j.steroids.2012.05.002

Reference yield: 69.0%

: 1000612-51-0
C₂₉H₄₃N₃O₃

: tomatidenol acetate

: 1415-78-7,6159-99-5
solasodine-3β-acetate

Guidance literature:: C₂₉H₄₃N₃O₃; With sodium iodide; In acetonitrile; for 0.5h; Inert atmosphere;

With chloro-trimethyl-silane; In acetonitrile; at 20 ℃; for 11h; Inert atmosphere;
DOI:10.1016/j.tetlet.2015.01.149

Reference yield:

: 1061-54-7
diosgenin acetate

: 1415-78-7,6159-99-5
solasodine-3β-acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium bromide; boron trifluoride diethyl etherate / dichloromethane; acetonitrile / 3 h / 25 °C / Inert atmosphere

1.2: 2 h / 65 °C / Inert atmosphere

2.1: sodium azide / 5 h / 60 °C / Inert atmosphere

3.1: sodium iodide / acetonitrile / 0.5 h / Inert atmosphere

3.2: 11 h / 20 °C / Inert atmosphere

With sodium azide; boron trifluoride diethyl etherate; sodium iodide; lithium bromide; In dichloromethane; acetonitrile;
DOI:10.1016/j.tetlet.2015.01.149