4-(Hydroxyamino)quinoline 1-oxide

Base Information

• Chemical Name: 4-(Hydroxyamino)quinoline 1-oxide
• CAS No.: 4637-56-3
• Molecular Formula: C9H8N2O2
• Molecular Weight: 176.19
• Hs Code.: 2933499090
• European Community (EC) Number: 679-909-5
• Nikkaji Number: J2.218G
• Mol file: 4637-56-3.mol

Synonyms:4 Hydroxyaminoquinoline 1 oxide;4 Hydroxyaminoquinoline N oxide;4-Hydroxyaminoquinoline-1-oxide;4-Hydroxyaminoquinoline-N-oxide

Chemical Property of 4-(Hydroxyamino)quinoline 1-oxide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 214oC
• Refractive Index: 1.5570 (estimate)
• Boiling Point: 342.2°Cat760mmHg
• PKA: 8.59±0.30(Predicted)
• Flash Point: 160.8°C
• PSA: 57.72000
• Density: 1.35g/cm³
• LogP: 2.14240
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 176.058577502
• Heavy Atom Count: 13
• Complexity: 250

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Hydroxyaminoquinoline-1-oxide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 45-46-25-37/38-41-68
• Safety Statements: 53-26-36/37/39-45

MSDS Files:

Useful:

• Chemical Classes: Other Uses -> Biochemical Research
• Canonical SMILES: C1=CC=C2C(=C1)C(=NO)C=CN2O

Technology Process of 4-(Hydroxyamino)quinoline 1-oxide

There total 4 articles about 4-(Hydroxyamino)quinoline 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitroquinoline-N-oxide (56-57-5) → 4-(hydroxyamino)quinoline N-oxide (4637-56-3)

Guidance literature:

With ethanol; palladium; Hydrogenation;

Reference yield:

4-Chloroquinoline N-oxide (4637-59-6) → 4-(hydroxyamino)quinoline N-oxide (4637-56-3)

Guidance literature:

Reference yield:

4-nitroquinoline-N-oxide (56-57-5) + ethanol (64-17-5) → 4-(hydroxyamino)quinoline N-oxide (4637-56-3)

Guidance literature:

Hydrogenation;

upstream raw materials:

4-nitroquinoline-N-oxide

4-Chloroquinoline N-oxide

ethanol

Downstream raw materials:

[4,4']azoxyquinoline-1,1'-dioxide