2-(4-Hydroxyphenylazo)benzoic acid

Base Information

• Chemical Name: 2-(4-Hydroxyphenylazo)benzoic acid
• CAS No.: 1634-82-8
• Molecular Formula: C13H10N2O3
• Molecular Weight: 242.234
• Hs Code.: 29270000
• European Community (EC) Number: 216-655-2
• NSC Number: 77376
• DSSTox Substance ID: DTXSID9061837
• Nikkaji Number: J7.539F
• Wikidata: Q27455492,Q106890864,Q27097088
• Metabolomics Workbench ID: 63335
• ChEMBL ID: CHEMBL1442125
• Mol file: 1634-82-8.mol

Synonyms:Benzoicacid, 2-[(4-hydroxyphenyl)azo]- (9CI);Benzoic acid, o-[(p-hydroxyphenyl)azo]-(6CI,7CI,8CI);2-(4-Hydroxybenzeneazo)benzoic acid;2-(4'-Hydroxybenzeneazo)benzoic acid;2-(4'-Hydroxyphenylazo)benzoic acid;2-[(4-Hydroxyphenyl)azo]benzoic acid;4-(2'-Carboxyphenylazo)phenol;4-Hydroxyazobenzene-2'-carboxylic acid;4'-Hydroxyazobenzene-2-carboxylic acid;HABA;HABA (dye);NSC 77376;o-(p-Hydroxyphenylazo)benzoic acid;

Chemical Property of 2-(4-Hydroxyphenylazo)benzoic acid

Chemical Property:

• Appearance/Colour: light yellow to orange powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 204-208 °C(lit.)
• Refractive Index: 1.627
• Boiling Point: 493.995 °C at 760 mmHg
• PKA: 3.40±0.36(Predicted)
• Flash Point: 252.559 °C
• PSA: 82.25000
• Density: 1.3g/cm³
• LogP: 3.50580
• Storage Temp.: Store below +30°C.
• Solubility.: ethanol: 20 mg/mL, clear
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 242.06914219
• Heavy Atom Count: 18
• Complexity: 311

Purity/Quality:

98%,99%, ^*data from raw suppliers

4'-Hydroxyazobenzene-2-carboxylic Acid [Matrix for MALDI-TOF/MS] >98.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)O)N=NC2=CC=C(C=C2)O
• Uses: 2-(4-Hydroxyphenylazo)benzoic acid may be used in the preparation of:2-((4-(3,4-dicyanophenoxy)phenyl)diazenyl)benzoic acid2,2′-((((4,5-dicyano-1,2-phenylene)bis(oxy))bis(4,1-phenylene))bis(diazene-2,1-diyl)) dibenzoic acida multifunctional benzoxazine monomer

Technology Process of 2-(4-Hydroxyphenylazo)benzoic acid

There total 11 articles about 2-(4-Hydroxyphenylazo)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

HABA valerate → 2-(4'-hydroxyphenylazo)benzoic acid (1634-82-8)

Guidance literature:

With BisTris buffer; N,N-dimethyl-formamide; sodium chloride; In water; at 25 ℃; Rate constant; avidin;

DOI:10.1021/ja00137a031

Reference yield:

HABA acetate → 2-(4'-hydroxyphenylazo)benzoic acid (1634-82-8) + acetic acid (64-19-7,77671-22-8)

Guidance literature:

With tetrahydrofuran; sodium hydroxide; phosphate buffer; sodium chloride; In water; at 20 ℃; Kinetics; avidin; also with biotin;

DOI:10.1021/ja00137a031

Reference yield:

→ 2-(4'-hydroxyphenylazo)benzoic acid (1634-82-8)

Guidance literature:

upstream raw materials:

o-Carboxybenzenediazonium

phenol

anthranilic acid

Downstream raw materials:

2-(4-methoxy-phenylazo)-benzoic acid

4-amino-phenol

anthranilic acid

2-(4-methoxy-phenylazo)-benzoic acid methyl ester