N-[2-(2-oxopyrrolidin-1-yl)ethyl]benzamide

Base Information

Chemical Name:N-[2-(2-oxopyrrolidin-1-yl)ethyl]benzamide
CAS No.:92884-72-5
Molecular Formula:C₁₃H₁₆N₂O₂
Molecular Weight:232.282
Hs Code.:
DSSTox Substance ID:DTXSID30358147
Wikidata:Q82138479

Synonyms:N-[2-(2-oxopyrrolidin-1-yl)ethyl]benzamide;92884-72-5;N-(2-(2-Oxopyrrolidin-1-yl)ethyl)benzamide;CBMicro_003741;Cambridge id 6046629;Oprea1_558100;SCHEMBL1402561;DTXSID30358147;SMSF0012163;AKOS024367319;CB05526;BIM-0003711.P001;SR-01000226002;SR-01000226002-1

Suppliers and Price of N-[2-(2-oxopyrrolidin-1-yl)ethyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-(2-oxopyrrolidin-1-yl)ethyl]benzamide

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:232.121177757
Heavy Atom Count:17
Complexity:285

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1)CCNC(=O)C2=CC=CC=C2

Technology Process of N-[2-(2-oxopyrrolidin-1-yl)ethyl]benzamide

There total 2 articles about N-[2-(2-oxopyrrolidin-1-yl)ethyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 24935-08-8
1-(2-aminoethyl)-2-pyrrolidinone

: 98-88-4
benzoyl chloride

: 92884-72-5
1-<2-(N-Benzoyl)aminoethyl>-2-oxopyrrolidine

Guidance literature:: With sodium hydroxide; for 2.5h; Ambient temperature;
DOI:10.1007/BF00769803

Reference yield:

: 57275-83-9
nitrile of 2-oxopyrrolidine-1-acetic acid

: 92884-72-5
1-<2-(N-Benzoyl)aminoethyl>-2-oxopyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / NaBH₄ / Raney nickel / aq. NaOH; methanol / 0.67 h / Ambient temperature

2: 85 percent / aq. NaOH / 2.5 h / Ambient temperature

With sodium hydroxide; sodium tetrahydroborate; nickel; In methanol; sodium hydroxide;
DOI:10.1007/BF00769803