3',4'-Dimethoxystilbene-4-ol

Base Information

• Chemical Name: 3',4'-Dimethoxystilbene-4-ol
• CAS No.: 128294-47-3
• Molecular Formula: C16H16 O3
• Molecular Weight: 256.301
• Nikkaji Number: J2.484.746B,J303.861K
• ChEMBL ID: CHEMBL231936
• Mol file: 128294-47-3.mol

Synonyms:Phenyl, 4-((1E)-2-(3,4-dimethoxyphenyl)ethenyl)-;128294-47-3;CHEMBL231936;SCHEMBL1815698;3',4'-Dimethoxystilbene-4-ol;(E)-3',4'-Dimethoxystilbene-4-ol

Chemical Property of 3',4'-Dimethoxystilbene-4-ol

Chemical Property:

• Vapor Pressure: 2.16E-07mmHg at 25°C
• Boiling Point: 412.5°Cat760mmHg
• Flash Point: 203.3°C
• Density: 1.169g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 256.109944368
• Heavy Atom Count: 19
• Complexity: 282

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C=CC2=CC=C(C=C2)O)OC
• Isomeric SMILES: COC1=C(C=C(C=C1)/C=C/C2=CC=C(C=C2)O)OC

Technology Process of 3',4'-Dimethoxystilbene-4-ol

There total 8 articles about 3',4'-Dimethoxystilbene-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(E)-1-(4'-acetoxyphenyl)-2-(3,4-dimethoxyphenyl)ethene (880354-47-2) → (E)-4-<2-(3,4-dimethoxyphenyl)ethenyl>phenol (128294-47-3)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; for 2h; Heating;

DOI:10.1016/j.tetlet.2008.07.087

Reference yield: 83.0%

(Z)-2-(4'-acetoxyphenyl)-3-(3,4-dimethoxyphenyl) acrylic acid → (E)-4-<2-(3,4-dimethoxyphenyl)ethenyl>phenol (128294-47-3)

Guidance literature:

With copper; sodium hydroxide; In quinoline; at 210 ℃; Inert atmosphere;

Reference yield: 41.0%

4-hydroxyphenylacetate (156-38-7) + 3,4-dimethoxy-benzaldehyde (120-14-9) → (E)-4-<2-(3,4-dimethoxyphenyl)ethenyl>phenol (128294-47-3)

Guidance literature:

With piperidine; 1-methyl-1H-imidazole; In various solvent(s); at 160 ℃; for 0.166667h; microwave irradiation;

DOI:10.1016/j.tet.2007.08.034

upstream raw materials:

4-hydroxyphenylacetate

3,4-dimethoxy-benzaldehyde

(E)-1-(4'-acetoxyphenyl)-2-(3,4-dimethoxyphenyl)ethene

p-acetoxystyrene

Downstream raw materials:

C₁₉H₂₁NO₃S

trans-3',4'-dimethoxy-4-mercaptostilbene

C₁₉H₂₁NO₃S

C₃₂H₃₀O₆