4H-Imidazo(4,5-c)(1,8)naphthyridin-4-one, 3,5-dihydro-5-butyl-3-methyl-

Base Information

Chemical Name:4H-Imidazo(4,5-c)(1,8)naphthyridin-4-one, 3,5-dihydro-5-butyl-3-methyl-
CAS No.:139482-29-4
Molecular Formula:C₁₄H₁₆N₄O
Molecular Weight:256.307
Hs Code.:
DSSTox Substance ID:DTXSID20161066
Nikkaji Number:J527.656J
Wikidata:Q83029431
ChEMBL ID:CHEMBL143079
Mol file:139482-29-4.mol

Synonyms:5-Butyl-3-methyl-3H-imidazo(4,5-c)(1,8)naphthyridin-4(5H)-one;4H-Imidazo(4,5-c)(1,8)naphthyridin-4-one, 3,5-dihydro-5-butyl-3-methyl-;CHEMBL143079;3,5-Dihydro-5-butyl-3-methyl-4H-imidazo(4,5-c)(1,8)naphthyridin-4-one;139482-29-4;SCHEMBL7282135;DTXSID20161066;XWCPJDLITHFYQE-UHFFFAOYSA-N;BDBM50230282;LS-79997;5-n-Butyl-3-methyl-3H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one;3-Methyl-5-butyl-3,5-dihydro-4H-imidazo[4,5-c][1,8]naphthyridin-4-one

Suppliers and Price of 4H-Imidazo(4,5-c)(1,8)naphthyridin-4-one, 3,5-dihydro-5-butyl-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4H-Imidazo(4,5-c)(1,8)naphthyridin-4-one, 3,5-dihydro-5-butyl-3-methyl-

Chemical Property:

Vapor Pressure:2E-11mmHg at 25°C
Boiling Point:532.7°Cat760mmHg
Flash Point:275.9°C
Density:1.28g/cm³
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:256.13241115
Heavy Atom Count:19
Complexity:348

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCN1C2=C(C=CC=N2)C3=C(C1=O)N(C=N3)C

Technology Process of 4H-Imidazo(4,5-c)(1,8)naphthyridin-4-one, 3,5-dihydro-5-butyl-3-methyl-

There total 7 articles about 4H-Imidazo(4,5-c)(1,8)naphthyridin-4-one, 3,5-dihydro-5-butyl-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 5-n-Butyl-3H-imidazo[4,5-c][1,8]naphthyridin-4(5H)-one

: 139482-29-4
5-butyl-3-methyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one

Guidance literature:

Reference yield:

: 145255-82-9
N-butyl-3-azaisatoic anhydride

: 139482-29-4
5-butyl-3-methyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) NaH / 1.) dimethylacetamide, 2.) dimethylacetamide, 170 deg C, 2 h

2: POCl₃ / 0.5 h / Heating

3: 28percent aq. NH₃ / tetrahydrofuran / 1 h / Ambient temperature

4: sodium hydrosulfite / ethanol; H₂O / 1 h / 80 °C

5: 2 h / 150 °C

6: 1.) NaH / 1.) DMF, 2.) DMF, RT, 2 h

With ammonium hydroxide; sodium disulfite; sodium hydride; trichlorophosphate; In tetrahydrofuran; ethanol; water;
DOI:10.1021/jm00104a013

Reference yield:

: 139482-08-9
1-butyl-4-chloro-3-nitro-1,8-naphthyridin-2(1H)-one

: 139482-29-4
5-butyl-3-methyl-3H-imidazo<4,5-c><1,8>naphthyridin-4(5H)-one

Guidance literature:: Multi-step reaction with 4 steps

1: 28percent aq. NH₃ / tetrahydrofuran / 1 h / Ambient temperature

2: sodium hydrosulfite / ethanol; H₂O / 1 h / 80 °C

3: 2 h / 150 °C

4: 1.) NaH / 1.) DMF, 2.) DMF, RT, 2 h

With ammonium hydroxide; sodium disulfite; sodium hydride; In tetrahydrofuran; ethanol; water;
DOI:10.1021/jm00104a013