Alanine, N-3-buten-1-yl-, methyl ester

Base Information

• Chemical Name: Alanine, N-3-buten-1-yl-, methyl ester
• CAS No.: 929277-14-5
• Molecular Formula: C8H15NO2
• Molecular Weight: 157.213
• Mol file: 929277-14-5.mol

Synonyms:

Chemical Property of Alanine, N-3-buten-1-yl-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Alanine, N-3-buten-1-yl-, methyl ester

There total 1 articles about Alanine, N-3-buten-1-yl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

Methyl 2-bromopropionate (5445-17-0) + 3-butene-1-amine (2524-49-4) → methyl 2-(N-but-3'-enylamino)propanoate (929277-14-5,709609-86-9)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; potassium carbonate; In acetonitrile; at 20 ℃; for 12h;

DOI:10.1021/jo061556t

Reference yield: 85.0%

methyl 2-(N-but-3'-enylamino)propanoate (929277-14-5,709609-86-9) + benzoyl chloride (98-88-4) → methyl 2-(N-benzoyl-N-but-3'-enylamino)propionate

Guidance literature:

With dmap; triethylamine; In diethyl ether; for 48h; Heating;

DOI:10.1021/jo061556t

Reference yield:

methyl 2-(N-but-3'-enylamino)propanoate (929277-14-5,709609-86-9) → 2-(N-benzoyl-N-but-3'-enylamino)propionic acid (929277-20-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / Et₃N; N,N-dimethylaminopyridine / diethyl ether / 48 h / Heating

2: 100 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 12 h / Heating

With dmap; lithium hydroxide; triethylamine; In tetrahydrofuran; diethyl ether; water;

DOI:10.1021/jo061556t

upstream raw materials:

Methyl 2-bromopropionate

3-butene-1-amine

Downstream raw materials:

2-(N-benzoyl-N-but-3'-enylamino)propionic acid