3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one

Base Information

Chemical Name:3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one
CAS No.:15584-10-8
Molecular Formula:C15H9 F O3
Molecular Weight:256.233
Hs Code.:2932999099
DSSTox Substance ID:DTXSID50165976
Nikkaji Number:J270.630J
Wikidata:Q83035233
ChEMBL ID:CHEMBL583378
Mol file:15584-10-8.mol

Synonyms:15584-10-8;3-(4-FLUOROPHENYL)-7-HYDROXY-4H-CHROMEN-4-ONE;3-(4-Fluoro-phenyl)-7-hydroxy-chromen-4-one;4'-fluoro-7-hydroxyisoflavone;3-(4-fluorophenyl)-7-hydroxychromen-4-one;BRN 1252082;3-(4-Fluorophenyl)-7-hydroxy-4H-1-benzopyran-4-one;Isoflavone, 4'-fluoro-7-hydroxy-;CHEMBL583378;3-(4-fluorophenyl)-7-hydroxy-4h-1-benzopyran-4-on;4H-1-Benzopyran-4-one, 3-(4-fluorophenyl)-7-hydroxy-;5-18-02-00278 (Beilstein Handbook Reference);C15H9FO3;Cambridge id 6942628;Oprea1_649229;Oprea1_652951;MLS000112963;SCHEMBL4683689;4''-fluoro-7-hydroxyisoflavone;4/'-Fluoro-7-hydroxyisoflavone;DTXSID50165976;HMS2504M22;BBL034771;BDBM50299415;STL421712;AKOS000122041;LS-39669;SMR000108870;VS-12663;CS-0268259;EN300-03237;SR-01000246727;SR-01000246727-1

Suppliers and Price of 3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one 97%
1g
$ 705.00

Chemenu
3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one 97%
1g
$ 666.00

American Custom Chemicals Corporation
3-(4-FLUORO-PHENYL)-7-HYDROXY-CHROMEN-4-ONE 95.00%
5G
$ 2012.49

American Custom Chemicals Corporation
3-(4-FLUORO-PHENYL)-7-HYDROXY-CHROMEN-4-ONE 95.00%
2.5G
$ 1527.20

American Custom Chemicals Corporation
3-(4-FLUORO-PHENYL)-7-HYDROXY-CHROMEN-4-ONE 95.00%
1G
$ 1012.63

Alichem
3-(4-Fluoro-phenyl)-7-hydroxy-chromen-4-one
250mg
$ 318.00

Alichem
3-(4-Fluoro-phenyl)-7-hydroxy-chromen-4-one
1g
$ 780.00

Total 2 raw suppliers

Chemical Property of 3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one

Chemical Property:

Vapor Pressure:1.76E-08mmHg at 25°C
Melting Point:235-236 °C
Boiling Point:443.6°Cat760mmHg
PKA:6.88±0.20(Predicted)
Flash Point:222.1°C
PSA：50.44000
Density:1.408g/cm³
LogP:3.30470
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:256.05357231
Heavy Atom Count:19
Complexity:385

Purity/Quality:

99% ^*data from raw suppliers

3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)F

Technology Process of 3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one

There total 17 articles about 3-(4-Fluorophenyl)-7-hydroxy-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 15485-70-8
4'-fluoro-2,4-dihydroxydeoxybenzoin

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 15584-10-8
7-hydroxy-3-(4'-fluorophenyl)-4H-1-benzopyran-4-one

Guidance literature:: With boron trifluoride diethyl etherate; phosphorus trichloride; at 50 - 60 ℃;
DOI:10.1007/BF00767029

Reference yield: 85.0%

: 1124174-57-7
4'-fluoro-7-(tetrahydropyran-2-yloxy)isoflavone

: 15584-10-8
7-hydroxy-3-(4'-fluorophenyl)-4H-1-benzopyran-4-one

Guidance literature:: With toluene-4-sulfonic acid; In tetrahydrofuran; methanol; at 20 - 60 ℃;
DOI:10.1021/jm900964r

Reference yield: 60.0%

: 15485-70-8
4'-fluoro-2,4-dihydroxydeoxybenzoin

: 124-63-0
methanesulfonyl chloride

: 15584-10-8
7-hydroxy-3-(4'-fluorophenyl)-4H-1-benzopyran-4-one

Guidance literature:: With boron trifluoride diethyl etherate; In N,N-dimethyl-formamide; at 60 - 95 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.bmcl.2018.10.021