2-Fluoro-3-methoxy-benzylamine

Base Information

• Chemical Name: 2-Fluoro-3-methoxy-benzylamine
• CAS No.: 93071-81-9
• Molecular Formula: C8H10FNO
• Molecular Weight: 155.172
• Hs Code.: 2921490090
• Mol file: 93071-81-9.mol

Synonyms:2-Fluoro-3-methoxybenzylamine;(2-FLUORO-3-METHOXYPHENYL)METHANAMINE;

Chemical Property of 2-Fluoro-3-methoxy-benzylamine

Chemical Property:

• Boiling Point: 237.4±25.0 °C (760 mmHg)
• PSA: 35.25000
• Density: 1.127±0.06 g/cm3(20 °C , 760mmHg)
• LogP: 1.99330
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99% ^*data from raw suppliers

(2-Fluoro-3-methoxyphenyl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Fluoro-3-methoxy-benzylamine

There total 4 articles about 2-Fluoro-3-methoxy-benzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2-fluoro-3-methoxybenzaldehyde oxime (1143571-79-2) → (2-fluoro-3-methoxyphenyl)methanamine (93071-81-9)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 2h;

Reference yield:

2-fluoro-3-methoxybenzaldehyde (103438-88-6) → (2-fluoro-3-methoxyphenyl)methanamine (93071-81-9)

Guidance literature:

2-fluoro-3-methoxybenzaldehyde; With hydrogenchloride; palladium 10% on activated carbon; In ethanol; water; at 20 ℃; for 2h;

With hydrogen; In ethanol; water; at 20 ℃; for 3h;

Reference yield:

(E)-2-fluoro-3-methoxybenzaldehyde oxime → (2-fluoro-3-methoxyphenyl)methanamine (93071-81-9)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 2h;

upstream raw materials:

2-fluoro-3-methoxybenzaldehyde

N-(2-fluoro-3-methoxyphenyl)methylphthalimide

2-fluoro-3-methoxybenzaldehyde oxime

Downstream raw materials:

2-fluoro-3-methoxybenzylamine hydrochloride

N-(2-fluoro-3-methoxyphenyl)methyl-2-amino-6-methylnicotinic acid amide