2-(4-Chlorophenyl)thiazolidine

Base Information

• Chemical Name: 2-(4-Chlorophenyl)thiazolidine
• CAS No.: 7738-99-0
• Molecular Formula: C9H10ClNS
• Molecular Weight: 199.7004
• Hs Code.: 2934999090
• NSC Number: 96377
• DSSTox Substance ID: DTXSID20875792
• Nikkaji Number: J48.804F
• Mol file: 7738-99-0.mol

Synonyms:2-(4-chlorophenyl)thiazolidine;2-(p-chlorophenyl)thiazolidine

Chemical Property of 2-(4-Chlorophenyl)thiazolidine

Chemical Property:

• Vapor Pressure: 0.000167mmHg at 25°C
• Boiling Point: 330.4°Cat760mmHg
• Flash Point: 153.6°C
• PSA: 37.33000
• Density: 1.245g/cm³
• LogP: 3.00380
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 199.0222482
• Heavy Atom Count: 12
• Complexity: 146

Purity/Quality:

98%min ^*data from raw suppliers

2-(4-Chloro-phenyl)-thiazolidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CSC(N1)C2=CC=C(C=C2)Cl

Technology Process of 2-(4-Chlorophenyl)thiazolidine

There total 3 articles about 2-(4-Chlorophenyl)thiazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-mercaptoethylamine hydrochloride (156-57-0) + 4-chlorobenzaldehyde (104-88-1) → 2-(4-chloro-phenyl)-thiazolidine (7738-99-0)

Guidance literature:

DOI:10.1021/jo01280a040

Reference yield:

4-chlorobenzaldehyde (104-88-1) + Cysteamine (60-23-1) → 2-(4-chloro-phenyl)-thiazolidine (7738-99-0)

Guidance literature:

Reference yield:

→ 2-(4-chloro-phenyl)-thiazolidine (7738-99-0)

Guidance literature:

/BRN= 190401/;

upstream raw materials:

2-mercaptoethylamine hydrochloride

4-chlorobenzaldehyde

Cysteamine

Downstream raw materials:

2-(4-Chloro-phenyl)-thiazolidine-3-carbothioic acid methylamide

2-(4-chloro-phenyl)-3-methyl-thiazolidine

2-(4-chloro-phenyl)-2,3-dimethyl-thiazolidine

Refernces

• 1、 Nate,Sekine,Honma,Nakai,Wada,Takeda,Yabana,Nagao. "Synthesis of 2-phenylthiazolidine derivatives as cardiotonic agents. I. 2-Phenylthiazolidine-3-thiocarboxamides.". . p. 1953 - 1968. Retrieved 2007/10/02.