Methanone, (2,3-dimethoxyphenyl)phenyl-

Base Information

• Chemical Name: Methanone, (2,3-dimethoxyphenyl)phenyl-
• CAS No.: 93081-14-2
• Molecular Formula: C15H14O3
• Molecular Weight: 242.274
• Mol file: 93081-14-2.mol

Synonyms:

Chemical Property of Methanone, (2,3-dimethoxyphenyl)phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methanone, (2,3-dimethoxyphenyl)phenyl-

There total 8 articles about Methanone, (2,3-dimethoxyphenyl)phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

Phenyl triflate (17763-67-6) + 2,3-dimethyoxybenzaldehyde (86-51-1) → 2,3-dimethoxybenzophenone (93081-14-2)

Guidance literature:

With 2,2,6,6-tetramethyl-piperidine; bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine]; In toluene; at 110 ℃; for 20h; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201710241

Reference yield:

(2,3-dimethoxyphenyl)(phenyl)methanol (56139-07-2) → 2,3-dimethoxybenzophenone (93081-14-2)

Guidance literature:

With potassium dichromate; sulfuric acid;

DOI:10.1039/jr9360000346

Reference yield:

2,3-dimethyoxybenzaldehyde (86-51-1) → 2,3-dimethoxybenzophenone (93081-14-2)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 2 h / Heating

2: Na₂Cr₂O₇; aq. H₂SO₄ / acetone / 3 h / 20 °C

With sodium dichromate; sulfuric acid; In diethyl ether; acetone; 2: Jones oxidation;

DOI:10.1021/ja052326j

upstream raw materials:

(2,3-dimethoxyphenyl)(phenyl)methanol

2,3-dimethoxybenzonitrile

2,3-dimethyoxybenzaldehyde

Phenyl triflate

Downstream raw materials:

(2,3-Dimethoxy-phenyl)-diphenyl-methanol

2,3-dihydroxybenzophenone

2-benzoyl-3,4-dimethoxy-benzoic acid

1-<2,3-Dimethoxy-phenyl>-N-formyl-1-phenyl-methylamin