1H-Isoindole-1,3(2H)-dione, 2-(2-(5-chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzimidazol-1-yl)ethyl)-

Base Information

Chemical Name:1H-Isoindole-1,3(2H)-dione, 2-(2-(5-chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzimidazol-1-yl)ethyl)-
CAS No.:79759-56-1
Molecular Formula:C23H16ClN3O3
Molecular Weight:417.8444
Hs Code.:
DSSTox Substance ID:DTXSID40229879
Wikidata:Q83110249

Synonyms:BRN 5649145;1H-Isoindole-1,3(2H)-dione, 2-(2-(5-chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzimidazol-1-yl)ethyl)-;1-Phthalimidoethyl-3-phenyl-5-chloro-benzimidazolin-2-one;79759-56-1;C23H16ClN3O3;DTXSID40229879;C23-H16-Cl-N3-O3;LS-84518

Suppliers and Price of 1H-Isoindole-1,3(2H)-dione, 2-(2-(5-chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzimidazol-1-yl)ethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Isoindole-1,3(2H)-dione, 2-(2-(5-chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzimidazol-1-yl)ethyl)-

Chemical Property:

Vapor Pressure:7.11E-15mmHg at 25°C
Boiling Point:611.1°Cat760mmHg
Flash Point:323.4°C
Density:1.443g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:417.0880191
Heavy Atom Count:30
Complexity:686

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C3=C(C=CC(=C3)Cl)N(C2=O)CCN4C(=O)C5=CC=CC=C5C4=O

Technology Process of 1H-Isoindole-1,3(2H)-dione, 2-(2-(5-chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzimidazol-1-yl)ethyl)-

There total 5 articles about 1H-Isoindole-1,3(2H)-dione, 2-(2-(5-chloro-2-oxo-3-phenyl-2,3-dihydro-1H-benzimidazol-1-yl)ethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1074-82-4
potassium phtalimide

: 79759-55-0
1-chloroethyl-3-phenyl-5-chloro-benzimidazolin-2-one

: 79759-56-1
1-phthalimidoethyl-3-phenyl-5-chloro-benzimidazolin-2-one

Guidance literature:: In N,N-dimethyl-formamide; at 80 - 100 ℃; for 10h;

Reference yield:

: 68406-47-3
4-chloro-N₂-phenylbenzene-1,2-diamine

: 79759-56-1
1-phthalimidoethyl-3-phenyl-5-chloro-benzimidazolin-2-one

Guidance literature:: Multi-step reaction with 5 steps

1: 86 percent / CHCl₃ / 20 h / Heating

2: 99.3 percent / EtONa / ethanol / 3 h / Heating

3: 90 percent / K₂CO₃ / methanol / 12 h / 50 - 55 °C

4: 88 percent / SOCl₂ / 7 h / Heating

5: 70 percent / dimethylformamide / 10 h / 80 - 100 °C

With thionyl chloride; sodium ethanolate; potassium carbonate; In methanol; ethanol; chloroform; N,N-dimethyl-formamide;

Reference yield:

: 79759-11-8
N¹-phenyl-N²-carbethoxy-5-chloro-o.phenylenediamine

: 79759-56-1
1-phthalimidoethyl-3-phenyl-5-chloro-benzimidazolin-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: 99.3 percent / EtONa / ethanol / 3 h / Heating

2: 90 percent / K₂CO₃ / methanol / 12 h / 50 - 55 °C

3: 88 percent / SOCl₂ / 7 h / Heating

4: 70 percent / dimethylformamide / 10 h / 80 - 100 °C

With thionyl chloride; sodium ethanolate; potassium carbonate; In methanol; ethanol; N,N-dimethyl-formamide;