1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide

Base Information

• Chemical Name: 1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide
• CAS No.: 93100-99-3
• Molecular Formula: C₁₉H₂₁ClN₂O₂S
• Molecular Weight: 376.907
• Hs Code.: 2935009090
• Mol file: 93100-99-3.mol

Synonyms:UNII-AW2Z8RD4XK;AW2Z8RD4XK;W 15;1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide;93100-99-3;W-15;(NE)-4-chloro-N-[1-(2-phenylethyl)piperidin-2-ylidene]benzenesulfonamide;AKOS017344863;(NE)-4-chloro-N-(1-phenethyl-2-piperidylidene)benzenesulfonamide

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of 1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide

Chemical Property:

• Boiling Point: 530.2±60.0 °C(Predicted)
• PKA: -0.54±0.20(Predicted)
• PSA: 58.12000
• Density: 1.26
• LogP: 5.17450
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 376.1012268
• Heavy Atom Count: 25
• Complexity: 544

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(C(=NS(=O)(=O)C2=CC=C(C=C2)Cl)C1)CCC3=CC=CC=C3
• Isomeric SMILES: C1CCN(/C(=N/S(=O)(=O)C2=CC=C(C=C2)Cl)/C1)CCC3=CC=CC=C3
• Description: W-15 (Item No. 14898) is an analytical reference material categorized as an analgesic. This product is intended for research and forensic applications.

Technology Process of 1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide

There total 1 articles about 1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

p-chlorobenzenesulfonyl azide (4547-68-6) + 1-(2-phenylethyl)-1,2,3,4-tetrahydropyridine (93101-19-0) → 1-(2-phenylethyl)piperidylidene-2-(4-chlorophenyl)sulfonamide (93100-99-3)

Guidance literature:

In diethyl ether; at 25 ℃; for 1h;

Reference yield: 61.0%

1-(2-phenylethyl)piperidylidene-2-(4-chlorophenyl)sulfonamide (93100-99-3) → 1-<2-(4-nitrophenyl)ethyl>piperidylidene-2-(4-chlorophenyl)sulfonamide (93101-02-1)

Guidance literature:

With nitric acid; at 25 ℃; for 4h;

Reference yield:

1-(2-phenylethyl)piperidylidene-2-(4-chlorophenyl)sulfonamide (93100-99-3) → 1-<2-(4-aminophenyl)ethyl>piperidylidene-2-(4-chlorophenyl)sulfonamide (93101-03-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / 90percent HNO₃ / 4 h / 25 °C

2: 67 percent / 85percent hydrazine hydrate / 10percent Pd/C / ethanol / 20 h / 25 °C

With nitric acid; hydrazine hydrate; palladium on activated charcoal; In ethanol;

upstream raw materials:

p-chlorobenzenesulfonyl azide

1-(2-phenylethyl)-1,2,3,4-tetrahydropyridine

Downstream raw materials:

1-<2-(4-nitrophenyl)ethyl>piperidylidene-2-(4-chlorophenyl)sulfonamide

1-<2-(4-aminophenyl)ethyl>piperidylidene-2-(4-chlorophenyl)sulfonamide