Benzene, 3-octynyl-

Base Information

• Chemical Name: Benzene, 3-octynyl-
• CAS No.: 93184-61-3
• Molecular Formula: C14H18
• Molecular Weight: 186.297
• Mol file: 93184-61-3.mol

Synonyms:

Chemical Property of Benzene, 3-octynyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, 3-octynyl-

There total 11 articles about Benzene, 3-octynyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-phenyl-2-bromoethane (103-63-9) + hex-1-yne (693-02-7) → oct-3-yn-1-ylbenzene (93184-61-3)

Guidance literature:

With copper(l) iodide; C₂₀H₂₃BrN₄Ni; caesium carbonate; sodium iodide; In dimethyl sulfoxide; at 100 ℃; for 16h; Inert atmosphere; Schlenk technique;

DOI:10.1039/C8NJ02138D

Reference yield: 84.0%

4-Phenyl-1-butyne (16520-62-0) + butyl triflate (75618-25-6) → oct-3-yn-1-ylbenzene (93184-61-3)

Guidance literature:

With zinc(II) bis(nonafluorobutanesulfonyl)imide; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; In toluene; at 50 ℃; for 24h; chemoselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1002/adsc.201801685

Reference yield: 70.0%

iodobenzene (591-50-4) + 3-Octynyllithium (129103-46-4) → oct-3-yn-1-ylbenzene (93184-61-3)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; zinc(II) chloride; at 25 ℃; for 1h;

DOI:10.1021/jo00306a022

upstream raw materials:

1-hexynyllithium

iodobenzene

3-Octynyllithium

1-Iodo-2-oct-3-ynyl-benzene