75618-25-6Relevant articles and documents
A SIMPLE SYNTHESIS OF ALLYLSILANES VIA TRISBORANE
Wang, Kung K.,Dhumrongvaraporn, Sujitra
, p. 1007 - 1010 (1987)
Allylsilanes were prepared by protonation or alkylation of lithium 1-alkynyltrisborates followed by protonolysis or treatment with aqueous sodium hydroxide and iodine.
Tuning the biological activity of cationic anthraquinone analogues specifically toward Staphylococcus aureus
Subedi, Yagya Prasad,Alfindee, Madher N.,Shrestha, Jaya P.,Chang, Cheng-Wei Tom
, p. 683 - 690 (2018/08/23)
Development of new antibacterial agents against drug resistant bacteria is an imminent task, especially against methicillin-resistant Staphylococcus aureus (MRSA). While MRSA can still be treated with broad spectrum antibiotics, the use of which often leads to the disruption of normal microbial flora leading to Clostridium difficile infection (CDI). Herein, a new class of antibacterial agent, cationic anthraquinone analogues specifically against MRSA, has been developed. Through the variation and optimization of substituents, these agents are selective toward MRSA, and not Gram negative bacteria which may avoid the problem of CDI. In addition, newly discovered lead compounds also show significantly reduced cytotoxicity against normal mammalian cells than cancerous cells. This interesting finding can alleviate the toxicity and side effect problems often associate with the use of antibiotics.
DERIVATIVES OF ELASTIN-LIKE POLYPEPTIDES AND USES THEREOF
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Page/Page column 18, (2017/02/28)
The present invention concerns the use of a thioether alkylation process for modulating the lower critical solution temperature of an elastin-like polypeptide comprising at least one methionine residue. It also concerns derivatives of elastin-like polypeptides and their preparation process.
