8-N3-cAMP

Base Information

• Chemical Name: 8-N3-cAMP
• CAS No.: 31966-52-6
• Molecular Formula: C₁₀H₁₁N₈O₆P
• Molecular Weight: 370.221
• Hs Code.: 29389090
• DSSTox Substance ID: DTXSID70953852
• Nikkaji Number: J392.513G
• Wikidata: Q76010049
• ChEMBL ID: CHEMBL3272800
• Mol file: 31966-52-6.mol

Synonyms:8-azido-cyclic AMP;8-azidoadenosine-3',5'-monophosphate;8-N3-cAMP

Chemical Property of 8-N3-cAMP

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Storage Temp.: −20°C
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 2
• Exact Mass: 370.05391710
• Heavy Atom Count: 25
• Complexity: 635

Purity/Quality:

98%Min ^*data from raw suppliers

8-Azidoadenosine 3',5'-cyclic monophosphosphate free acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C2C(C(C(O2)N3C4=NC=NC(=C4N=C3N=[N+]=[N-])N)O)OP(=O)(O1)O
• Isomeric SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=NC=NC(=C4N=C3N=[N+]=[N-])N)O)OP(=O)(O1)O
• Uses: 8-Azidoadenosine 3'':5''-Cyclic Monophosphate is a photoaffinity label for cAMP-dependent enzymes. Specifically it has shown its utility as a phtoaffinity probe for cAMP binding sites in human erythrocyte membranes.

Technology Process of 8-N3-cAMP

There total 1 articles about 8-N3-cAMP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 8-azidoadenosine 3',5'-cyclic monophosphate (31966-52-6)

Guidance literature:

Aus der 8-Bromverb. mit NaN3;

DOI:10.1021/bi00788a033

Reference yield:

8-azidoadenosine 3',5'-cyclic monophosphate (31966-52-6) + 4-(2,2-difluoro-cyclooct-3-ynylmethyl)-benzoic acid (1047997-30-7) → C26H27F2N8O8P

Guidance literature:

at 37 ℃; for 5h;

DOI:10.3390/molecules181012909

Refernces