2,4-Thiazolidinedithione

Base Information

• Chemical Name: 2,4-Thiazolidinedithione
• CAS No.: 4303-27-9
• Molecular Formula: C3H3NS3
• Molecular Weight: 149.262
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID70406277
• Nikkaji Number: J2.006.250I
• Wikidata: Q82211183
• Mol file: 4303-27-9.mol

Synonyms:2,4-Thiazolidinedithione;4303-27-9;1,3-thiazolidine-2,4-dithione;thiazolidine-2,4-dithione;thiorhodanine;2,4-dithioxo-thiazolidine;thiazolidine -2,4-dithione;SCHEMBL497077;DTXSID70406277;VIYJCVXSZKYVBL-UHFFFAOYSA-N;AMY21570;AKOS002663598;A934496

Chemical Property of 2,4-Thiazolidinedithione

Chemical Property:

• Melting Point: 81-83 °C
• Boiling Point: 223.2±23.0 °C(Predicted)
• PKA: 7.05±0.20(Predicted)
• PSA: 108.55000
• Density: 1.62±0.1 g/cm3(Predicted)
• LogP: 0.78200
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 148.94276262
• Heavy Atom Count: 7
• Complexity: 119

Purity/Quality:

95% ^*data from raw suppliers

Thiazolidine-2,4-dithione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(=S)NC(=S)S1

Technology Process of 2,4-Thiazolidinedithione

There total 2 articles about 2,4-Thiazolidinedithione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-thioxo-4-thiazolidinone (141-84-4) → 2,4-dithioxothiazolidine (4303-27-9)

Guidance literature:

With tetraphosphorus decasulfide; In 1,4-dioxane; Heating;

DOI:10.1007/BF00742364

Reference yield:

→ 2,4-dithioxothiazolidine (4303-27-9)

Guidance literature:

Rhodanin, P2S5;

Reference yield: 91.0%

2-fluoro-5-methoxybenzaldehyde (105728-90-3) + 2,4-dithioxothiazolidine (4303-27-9) → 5-(2-fluoro-5-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one

Guidance literature:

With ammonium acetate; In acetic acid; toluene; at 120 ℃; for 12h;

upstream raw materials:

2-thioxo-4-thiazolidinone

Downstream raw materials:

4-(4-methoxy-anilino)-5H-thiazole-2-thione

2-thioxo-thiazolidine-4-one benzoylhydrazone

2,4-dithioxo-thiazolidin-5-one phenylhydrazone

5-(2-nitro-benzylidene)-thiazolidine-2,4-dithione