Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(4-chlorophenyl 1H-1,2,4-triazol-1-ylphosphonate)

Base Information

Chemical Name:Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(4-chlorophenyl 1H-1,2,4-triazol-1-ylphosphonate)
CAS No.:93403-73-7
Molecular Formula:C₃₉H₃₇ClN₅O₉P
Molecular Weight:786.178
Hs Code.:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(4-chlorophenyl 1H-1,2,4-triazol-1-ylphosphonate)

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Technology Process of Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(4-chlorophenyl 1H-1,2,4-triazol-1-ylphosphonate)

There total 5 articles about Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-(4-chlorophenyl 1H-1,2,4-triazol-1-ylphosphonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67221-57-2
5'-O-(dimethoxytrityl)thymidine 3'-(p-chlorphenylcyanoethyl phosphate)

: 93403-73-7
5'-O-(dimethoxytrityl)thymidine 3'-(p-chlorophenyl phosphoro-1,2,4-triazolide)

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine, water / pyridine / Ambient temperature

2: 1.) pyridine, 5 min, 2.) 6 h

With water; triethylamine; In pyridine;
DOI:10.1021/jo00199a039