2-(2,4-Dimethoxyphenyl)ethanol

Base Information

• Chemical Name: 2-(2,4-Dimethoxyphenyl)ethanol
• CAS No.: 13398-65-7
• Molecular Formula: C10H14 O3
• Molecular Weight: 182.219
• Hs Code.: 2909499000
• NSC Number: 101849
• DSSTox Substance ID: DTXSID30295427
• Nikkaji Number: J1.867.921C
• Wikidata: Q82035364
• Mol file: 13398-65-7.mol

Synonyms:2-(2,4-dimethoxyphenyl)ethanol;13398-65-7;2,4-Dimethoxyphenethyl alcohol;2-(2,4-dimethoxyphenyl)ethan-1-ol;NSC101849;NCIOpen2_001663;SCHEMBL48353;DTXSID30295427;2,4-Dimethoxyphenylmethyl carbinol;AKOS012095660;NSC-101849;2-(2,4-dimethoxyphenyl)ethanol, AldrichCPR;CS-0309162;F11610;EN300-1635478

Chemical Property of 2-(2,4-Dimethoxyphenyl)ethanol

Chemical Property:

• Vapor Pressure: 0.000705mmHg at 25°C
• Boiling Point: 295.1°Cat760mmHg
• Flash Point: 132.3°C
• PSA: 38.69000
• Density: 1.086g/cm³
• LogP: 1.23860
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 182.094294304
• Heavy Atom Count: 13
• Complexity: 138

Purity/Quality:

99% ^*data from raw suppliers

2-(2,4-DIMETHOXYPHENYL)ETHANOL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C=C1)CCO)OC

Technology Process of 2-(2,4-Dimethoxyphenyl)ethanol

There total 9 articles about 2-(2,4-Dimethoxyphenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-(2,4-dimethoxyphenyl)acetaldehyde (1057663-21-4) → 2,4-dimethoxy-phenethyl alcohol (13398-65-7)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1016/j.tet.2009.10.116

Reference yield: 90.0%

2,4-dimethoxystyrene (40243-84-3) → 2,4-dimethoxy-phenethyl alcohol (13398-65-7)

Guidance literature:

2,4-dimethoxystyrene; With 9-borabicyclo[3.3.1]nonane dimer;

With sodium hydroxide; dihydrogen peroxide; Further stages.;

DOI:10.1016/j.tetlet.2008.06.085

Reference yield:

C18H27BO2 → 2,4-dimethoxy-phenethyl alcohol (13398-65-7)

Guidance literature:

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 3h;

DOI:10.1016/j.tet.2009.10.116

upstream raw materials:

oxirane

1,3-Dimethoxybenzene

2,4-dimethoxyphenylacetic acid

ethene

Downstream raw materials:

2-(2,4-dimethoxyphenyl)acetaldehyde

1-(2-bromoethyl)-2,4-dimethoxybenzene

2,4-dimethoxyphenethyl acetate

2,4-Dimethoxybenzaldehyde

Refernces

• 1、 Takashima, Yuji,Kaneko, Yuki,Kobayashi, Yuichi. "Synthetic access to optically active isoflavans by using allylic substitution". experimental part. p. 197 - 207. Retrieved 2010/03/03.