N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]acetamide

Base Information

Chemical Name:N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]acetamide
CAS No.:34379-43-6
Molecular Formula:C₁₄H₂₃NO₆
Molecular Weight:301.34
Hs Code.:
NSC Number:51449

Synonyms:NSC51449;NSC-51449;34379-43-6

Suppliers and Price of N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 2 raw suppliers

Chemical Property of N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]acetamide

Chemical Property:

Vapor Pressure:7.67E-08mmHg at 25°C
Boiling Point:437.1°Cat760mmHg
Flash Point:218.2°C
Density:1.24g/cm³
XLogP3:0
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:301.15253745
Heavy Atom Count:21
Complexity:437

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1C(OC2C1OC(O2)(C)C)C3COC(O3)(C)C

Technology Process of N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]acetamide

There total 9 articles about N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 108-24-7
acetic anhydride

: 16848-19-4
1,2,5,6-di-O-isopropylidene-3-deoxy-3-amino-α-D-glucofuranoside

: 34379-43-6
3-acetamido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

Guidance literature:: With pyridine; In methanol; for 0.5h;
DOI:10.1016/0008-6215(91)80125-7

Reference yield: 68.0%

: 108-24-7
acetic anhydride

: 3-amino-3-deoxy-1,2:5,6-di-O-isopropylidene-D-glucofuranose

: 13964-24-4,19131-09-0,27581-58-4,34296-91-8,34379-43-6
3-acetamido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

Guidance literature:: With pyridine; at 0 ℃;
DOI:10.1007/s10719-011-9357-y

Reference yield:

: 10578-95-7
(E/Z)-3-Deoxy-3-hydroxyimino-1,2:5,6-di-O-isopropylidene-α-D-ribohexofuranose

: 34379-43-6
3-acetamido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / Et₃N / CH₂Cl₂; petroleum ether / 1 h / -30 °C

2: 86 percent / sodium borohydride / tetrahydrofuran / Ambient temperature

3: 0.21 g / pyridine / Ambient temperature

With pyridine; sodium tetrahydroborate; triethylamine; In tetrahydrofuran; dichloromethane; Petroleum ether;
DOI:10.1016/0008-6215(95)00256-1