1,2,5,6-di-O-isopropylidene-3-deoxy-3-amino-α-D-glucofuranoside

Base Information

• Chemical Name: 1,2,5,6-di-O-isopropylidene-3-deoxy-3-amino-α-D-glucofuranoside
• CAS No.: 16848-19-4
• Molecular Formula: C₁₂H₂₁NO₅
• Molecular Weight: 259.302
• Mol file: 16848-19-4.mol

Synonyms:1,2,5,6-di-O-isopropylidene-3-deoxy-3-amino-α-D-glucofuranoside

Chemical Property of 1,2,5,6-di-O-isopropylidene-3-deoxy-3-amino-α-D-glucofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,5,6-di-O-isopropylidene-3-deoxy-3-amino-α-D-glucofuranoside

There total 23 articles about 1,2,5,6-di-O-isopropylidene-3-deoxy-3-amino-α-D-glucofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-azido-3-deoxy-1,2:5,6-di-(O-isopropylidene)-α-D-glucofuranose (13964-23-3) → 3-amino-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (16848-19-4,24384-84-7,71165-01-0,71187-80-9,73881-34-2,91067-83-3)

Guidance literature:

With (Sn(SPh)3)(Et₃N); In benzene; at 15 ℃; for 0.0833333h; 1360;

DOI:10.1016/S0040-4039(01)81096-0

Reference yield: 97.0%

3-azido-3-deoxy-1,2:5,6-di-(O-isopropylidene)-α-D-glucofuranose (13964-23-3) → 3-amino-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranoside (16848-19-4,24384-84-7,71165-01-0,71187-80-9,73881-34-2,91067-83-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 1h; Heating;

Reference yield: 91.0%

(3aR,5S,6R,6aR)-6-Azido-5-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole → 3-amino-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranoside (16848-19-4,24384-84-7,71165-01-0,71187-80-9,73881-34-2,91067-83-3)

Guidance literature:

With ammonium chloride; indium; In ethanol; for 2h; Heating;

DOI:10.1016/S0040-4039(99)00614-0

upstream raw materials:

3-azido-3-deoxy-1,2:5,6-di-(O-isopropylidene)-α-D-glucofuranose

3β-<((trifluoromethyl)phenylmethyl)imino>-3-deoxy-1,2:5,6-di-O-isopropylidene-D-glucofuranose

D-Glucose

1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose

Downstream raw materials:

3-acetamido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose

O¹,O²;O⁵,O⁶-diisopropylidene-3-salicylideneamino-3-deoxy-α-D-allofuranose

3-benzoylamino-O¹,O^2;O⁵,O⁶-diisopropylidene-3-deoxy-α-D-allofuranose

3-amino-3-deoxy-D-allose