N-[1-(Benzyloxy)but-3-en-2-yl]-2,2,2-trichloroacetamide

Base Information

Chemical Name:N-[1-(Benzyloxy)but-3-en-2-yl]-2,2,2-trichloroacetamide
CAS No.:93667-62-0
Molecular Formula:C13H14Cl3NO2
Molecular Weight:322.619
Hs Code.:
DSSTox Substance ID:DTXSID50540123

Synonyms:N-[1-(Benzyloxy)but-3-en-2-yl]-2,2,2-trichloroacetamide;93667-62-0;SCHEMBL10823687;DTXSID50540123;ITMOKSPVTNBLJV-UHFFFAOYSA-N

Suppliers and Price of N-[1-(Benzyloxy)but-3-en-2-yl]-2,2,2-trichloroacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[1-(Benzyloxy)but-3-en-2-yl]-2,2,2-trichloroacetamide

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:321.009012
Heavy Atom Count:19
Complexity:299

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=CC(COCC1=CC=CC=C1)NC(=O)C(Cl)(Cl)Cl

Technology Process of N-[1-(Benzyloxy)but-3-en-2-yl]-2,2,2-trichloroacetamide

There total 6 articles about N-[1-(Benzyloxy)but-3-en-2-yl]-2,2,2-trichloroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 97186-53-3
(Z)-1-benzyloxy-4-trichloroacetimidoxybut-2-ene

: 93667-62-0
4-benzyloxy-3-trichloroacetamido-1-butene

Guidance literature:: In decalin; for 12h; Heating;

Reference yield: 86.0%

: 104808-53-9
1-(1-imino-2,2,2-trichloroethoxy)-4-benzyloxy-2(E)-butene

: 93667-62-0
4-benzyloxy-3-trichloroacetamido-1-butene

Guidance literature:: In xylene; at 150 ℃; for 52h;
DOI:10.1016/S0040-4020(02)00305-8

Reference yield:

: 80885-30-9,81028-03-7,69152-88-1
(E)-4-(benzyloxy)-2-buten-1-ol

: 93667-62-0
4-benzyloxy-3-trichloroacetamido-1-butene

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NAH / 1.) THF, 0 deg C, 1 h, 2.) THF, RT, 1.5 h

2: decahydronaphthalene / 12 h / Heating

With sodium hydride; In decalin;
DOI:10.1021/jo00355a023