2-(2,4-dichlorobenzoyl)-N-phenylhydrazinecarbothioamide

Base Information

• Chemical Name: 2-(2,4-dichlorobenzoyl)-N-phenylhydrazinecarbothioamide
• CAS No.: 93677-68-0
• Molecular Formula: C14H11Cl2N3OS
• Molecular Weight: 340.233
• European Community (EC) Number: 657-306-8
• Mol file: 93677-68-0.mol

Synonyms:2-(2,4-dichlorobenzoyl)-N-phenylhydrazinecarbothioamide;STL282679;AKOS002222252;2-[(2,4-dichlorophenyl)carbonyl]-N-phenylhydrazinecarbothioamide

Chemical Property of 2-(2,4-dichlorobenzoyl)-N-phenylhydrazinecarbothioamide

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 338.9999885
• Heavy Atom Count: 21
• Complexity: 377

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NC(=S)NNC(=O)C2=C(C=C(C=C2)Cl)Cl

Technology Process of 2-(2,4-dichlorobenzoyl)-N-phenylhydrazinecarbothioamide

There total 4 articles about 2-(2,4-dichlorobenzoyl)-N-phenylhydrazinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,4-dichlorobenzohydrazide (5814-06-2) + phenyl isothiocyanate (103-72-0) → 1-(2,4-Dichlorobenzoyl)-4-phenylthiosemicarbazide (93677-68-0)

Guidance literature:

In ethanol; for 6h; Heating;

DOI:10.1002/jhet.5570210460

Reference yield:

ethyl 2,4-dichlorobenzoate (56882-52-1) → 1-(2,4-Dichlorobenzoyl)-4-phenylthiosemicarbazide (93677-68-0)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 8 h / Heating

2: 85 percent / ethanol / 6 h / Heating

With hydrazine hydrate; In ethanol;

Reference yield:

2,4 dichlorobenzoic acid (50-84-0) → 1-(2,4-Dichlorobenzoyl)-4-phenylthiosemicarbazide (93677-68-0)

Guidance literature:

Multi-step reaction with 4 steps

1: thionyl chloride

3: hydrazine hydrate / ethanol / 8 h / Heating

4: 85 percent / ethanol / 6 h / Heating

With thionyl chloride; hydrazine hydrate; In ethanol;

upstream raw materials:

2,4-dichlorobenzohydrazide

phenyl isothiocyanate

2,4 dichlorobenzoic acid

ethyl 2,4-dichlorobenzoate

Downstream raw materials:

3-(2,4-Dichlorophenyl)-4-phenyl-1,2,4-triazole-5-thiol

5-(2,4-Dichloro-phenyl)-4-phenyl-2,4-dihydro-[1,2,4]triazole-3-thione

3-(2,4-Dichlorophenyl)-4-phenyl-5-methylthio-1,2,4-triazole