tetrahydro-2H-thiopyran 1,1-dioxide

Base Information

• Chemical Name: tetrahydro-2H-thiopyran 1,1-dioxide
• CAS No.: 4988-33-4
• Molecular Formula: C5H10O2S
• Molecular Weight: 134.199
• Mol file: 4988-33-4.mol

Synonyms:

Chemical Property of tetrahydro-2H-thiopyran 1,1-dioxide

Chemical Property:

• Vapor Pressure: 1.04mmHg at 25°C
• Boiling Point: 183.7°Cat760mmHg
• Flash Point: 44.4°C
• Density: 1.187g/cm³

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tetrahydro-2H-thiopyran 1,1-dioxide

There total 5 articles about tetrahydro-2H-thiopyran 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

hex-5-enoic acid 2-thioxo-2H-pyridin-1-yl ester (197148-70-2) → pentamethylene sulfone (4988-33-4) + 2-methyl sulfolane (1003-46-9)

Guidance literature:

hex-5-enoic acid 2-thioxo-2H-pyridin-1-yl ester; With sulfur dioxide; In dichloromethane; at -40 ℃; for 1h; Photolysis;

With sodium tetrahydroborate; nickel dichloride; In tetrahydrofuran; methanol; at 0 ℃; for 0.25h;

DOI:10.1021/jo052035t

Reference yield:

(but-3-ene-1-sulfonylmethylselanyl)-benzene (314056-83-2) → 3-methylsulfolane (872-93-5) + pentamethylene sulfone (4988-33-4)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃; for 0.0333333h;

DOI:10.1021/jo0497306

Reference yield:

(but-3-ene-1-sulfonylmethylselanyl)-benzene (314056-83-2) → 3-methylsulfolane (872-93-5) + pentamethylene sulfone (4988-33-4) + 4-(methylsulfonyl)but-1-ene

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 80 ℃; for 2h;

DOI:10.1016/S0040-4039(00)01377-0

upstream raw materials:

hydrogenchloride

1,1-dioxotetrahydrothiopyran-4-one

(but-3-ene-1-sulfonylmethylselanyl)-benzene

hex-5-enoic acid 2-thioxo-2H-pyridin-1-yl ester

Downstream raw materials:

2-phenyltetrahydro-2H-thiopyran 1,1-dioxide

N-[1-(tetrahydro-1,1-dioxido-2H-thiopyran-2(S)-yl)cyclohexyl]-2-methyl-2-propane-(S)-sulfinamide