(4aR,8aR)-7-methyl-1-(6-methylhept-5-en-2-yl)-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalene

Base Information

Chemical Name:(4aR,8aR)-7-methyl-1-(6-methylhept-5-en-2-yl)-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalene
CAS No.:95910-64-8
Molecular Formula:C20H32
Molecular Weight:272.4681
Hs Code.:

Synonyms:

Suppliers and Price of (4aR,8aR)-7-methyl-1-(6-methylhept-5-en-2-yl)-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4aR,8aR)-7-methyl-1-(6-methylhept-5-en-2-yl)-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalene

Chemical Property:

Vapor Pressure:7.02E-05mmHg at 25°C
Boiling Point:354°Cat760mmHg
Flash Point:160.1°C
Density:0.89g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4aR,8aR)-7-methyl-1-(6-methylhept-5-en-2-yl)-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalene

There total 67 articles about (4aR,8aR)-7-methyl-1-(6-methylhept-5-en-2-yl)-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2385-77-5
(R)-Citronellal

: 69636-81-3,74219-33-3,90457-78-6,90457-79-7,90457-80-0,90457-81-1,95910-64-8,104195-70-2,104195-71-3
(1S,6S,7S,11R)-(-)-biflora-4,10(19),15-triene

Guidance literature:: Multi-step reaction with 9 steps

1: 46.4 g / benzene / 3 h / Heating

2: 2.) AcOH / 1.) MeCN, 50 h, 80-81 deg C, 2.) water, 75-76 deg C, 2 h

3: 58 percent / NaH / dimethylsulfoxide / 1.33 h / 20 - 25 °C

4: 98.9 percent / LAH / diethyl ether / 1.) 35 min, 3-10 deg C, 2.) 30 min, room temp.

5: 88.8 percent / DCC, CF₃CO₂H, C₅H₅N, HO₂C-CO₂H*2H₂O / benzene; dimethylsulfoxide; methanol; diethyl ether / 0.33 h / 14 - 18 °C

6: 72.6 percent / tetrahydrofuran / 0.33 h / -67 °C

7: 86.5 percent / H₂, quinoline / Pd-BaSO₄ (5percent) / methanol / 4 h / 20 - 25 °C

8: CrO₃ H₂SO₄ / acetone / 0.17 h / 0 °C

9: n-BuLi / 1.) THF, 5 - 7 deg C, 30 min, 2.) 21 deg C, 30 min

With pyridine; quinoline; chromium(VI) oxide; lithium aluminium tetrahydride; n-butyllithium; sulfuric acid; hydrogen; oxalic acid; sodium hydride; acetic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on barium sulfate; In tetrahydrofuran; methanol; diethyl ether; dimethyl sulfoxide; acetone; benzene;
DOI:10.1016/S0040-4020(01)91176-7

Reference yield:

: 2385-77-5
(R)-Citronellal

: 69636-81-3,74219-33-3,90457-78-6,90457-79-7,90457-80-0,90457-81-1,95910-64-8,104195-70-2,104195-71-3
(1R,6S,7S,11R)-(+)-biflora-4,10(19),15-triene

Guidance literature:: Multi-step reaction with 10 steps

1: 46.4 g / benzene / 3 h / Heating

2: 2.) AcOH / 1.) MeCN, 50 h, 80-81 deg C, 2.) water, 75-76 deg C, 2 h

3: 58 percent / NaH / dimethylsulfoxide / 1.33 h / 20 - 25 °C

4: 98.9 percent / LAH / diethyl ether / 1.) 35 min, 3-10 deg C, 2.) 30 min, room temp.

5: 88.8 percent / DCC, CF₃CO₂H, C₅H₅N, HO₂C-CO₂H*2H₂O / benzene; dimethylsulfoxide; methanol; diethyl ether / 0.33 h / 14 - 18 °C

6: 72.6 percent / tetrahydrofuran / 0.33 h / -67 °C

7: 86.5 percent / H₂, quinoline / Pd-BaSO₄ (5percent) / methanol / 4 h / 20 - 25 °C

8: CrO₃ H₂SO₄ / acetone / 0.17 h / 0 °C

9: 2percent NaOMe / methanol / 1.5 h / Heating

10: n-BuLi / 1.) THF, 5 - 7 deg C, 2.) 21 deg C, 30 min

With pyridine; quinoline; chromium(VI) oxide; lithium aluminium tetrahydride; n-butyllithium; sulfuric acid; hydrogen; sodium methylate; oxalic acid; sodium hydride; acetic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on barium sulfate; In tetrahydrofuran; methanol; diethyl ether; dimethyl sulfoxide; acetone; benzene;
DOI:10.1016/S0040-4020(01)91176-7

Reference yield:

: 2385-77-5
(R)-Citronellal

: 69636-81-3,74219-33-3,90457-78-6,90457-79-7,90457-80-0,90457-81-1,95910-64-8,104195-70-2,104195-71-3
(1S,6R,7R,11R)-(-)-biflora-4,10(19),15-triene

Guidance literature:: Multi-step reaction with 10 steps

1: 46.4 g / benzene / 3 h / Heating

2: 2.) AcOH / 1.) MeCN, 50 h, 80-81 deg C, 2.) water, 75-76 deg C, 2 h

3: 58 percent / NaH / dimethylsulfoxide / 1.33 h / 20 - 25 °C

4: 98.9 percent / LAH / diethyl ether / 1.) 35 min, 3-10 deg C, 2.) 30 min, room temp.

5: 88.8 percent / DCC, CF₃CO₂H, C₅H₅N, HO₂C-CO₂H*2H₂O / benzene; dimethylsulfoxide; methanol; diethyl ether / 0.33 h / 14 - 18 °C

6: 72.6 percent / tetrahydrofuran / 0.33 h / -67 °C

7: 86.5 percent / H₂, quinoline / Pd-BaSO₄ (5percent) / methanol / 4 h / 20 - 25 °C

8: CrO₃ H₂SO₄ / acetone / 0.17 h / 0 °C

9: 2percent NaOMe / methanol / 2 h / Heating

10: n-BuLi / 1.) THF, 5 - 7 deg C, 2.) 21 deg C, 30 min

With pyridine; quinoline; chromium(VI) oxide; lithium aluminium tetrahydride; n-butyllithium; sulfuric acid; hydrogen; sodium methylate; oxalic acid; sodium hydride; acetic acid; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on barium sulfate; In tetrahydrofuran; methanol; diethyl ether; dimethyl sulfoxide; acetone; benzene;
DOI:10.1016/S0040-4020(01)91176-7