Ethanone, 1-[4-(2-methoxy-1-methylethyl)phenyl]-

Base Information

• Chemical Name: Ethanone, 1-[4-(2-methoxy-1-methylethyl)phenyl]-
• CAS No.: 94474-94-9
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol file: 94474-94-9.mol

Synonyms:

Chemical Property of Ethanone, 1-[4-(2-methoxy-1-methylethyl)phenyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanone, 1-[4-(2-methoxy-1-methylethyl)phenyl]-

There total 5 articles about Ethanone, 1-[4-(2-methoxy-1-methylethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2-(4-Acetylphenyl)-1-propanol (63519-71-1,133330-09-3) + dimethyl sulfate (77-78-1) → 2-p-acetylphenyl-1-propyl methyl ether (94474-94-9)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; 1.) petroleum ether, 30 min; 2.) 4 h;

DOI:10.1016/S0040-4020(01)87425-1

Reference yield:

2-Phenylpropanal (34713-70-7) → 2-p-acetylphenyl-1-propyl methyl ether (94474-94-9)

Guidance literature:

Multi-step reaction with 5 steps

1: 89 percent / sodium borohydride, 2 M NaOH / ethanol; H₂O / Ambient temperature

2: 73 percent / conc. sulphuric acid / toluene / 24 h / Heating

3: 68 percent / aluminium chloride / CH₂Cl₂ / 22 h / Ambient temperature

4: 63 percent / 20percent aq. Na₂CO₃ / 3 h / Ambient temperature

5: 52 percent / 1.) tetrabutylammonium iodide, 12 M NaOH / 1.) petroleum ether, 30 min; 2.) 4 h

With sodium hydroxide; sodium tetrahydroborate; aluminium trichloride; sulfuric acid; tetra-(n-butyl)ammonium iodide; sodium carbonate; In ethanol; dichloromethane; water; toluene;

DOI:10.1016/S0040-4020(01)87425-1

Reference yield:

(RS)-2-phenyl-1-propanol (1123-85-9) → 2-p-acetylphenyl-1-propyl methyl ether (94474-94-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 73 percent / conc. sulphuric acid / toluene / 24 h / Heating

2: 68 percent / aluminium chloride / CH₂Cl₂ / 22 h / Ambient temperature

3: 63 percent / 20percent aq. Na₂CO₃ / 3 h / Ambient temperature

4: 52 percent / 1.) tetrabutylammonium iodide, 12 M NaOH / 1.) petroleum ether, 30 min; 2.) 4 h

With sodium hydroxide; aluminium trichloride; sulfuric acid; tetra-(n-butyl)ammonium iodide; sodium carbonate; In dichloromethane; toluene;

DOI:10.1016/S0040-4020(01)87425-1

upstream raw materials:

2-(4-Acetylphenyl)-1-propanol

dimethyl sulfate

2-Phenylpropanal

(RS)-2-phenyl-1-propanol

Downstream raw materials:

2-p-acetoxyphenyl-1-propyl methyl ether