ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE

Base Information

• Chemical Name: ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE
• CAS No.: 32137-76-1
• Molecular Formula: C10H9NO2S
• Molecular Weight: 207.253
• Hs Code.: 29349990
• Mol file: 32137-76-1.mol

Synonyms:(2-Ethoxycarbonyl)benzothiazole;Ethyl 2-benzothiazolecarboxylate;Ethyl benzo[d]thiazole-2-carboxylate;

Chemical Property of ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE

Chemical Property:

• Vapor Pressure: 0.000519mmHg at 25°C
• Melting Point: 66-68 °C
• Refractive Index: 1.627
• Boiling Point: 312.8 °C at 760 mmHg
• PKA: -1.07±0.10(Predicted)
• Flash Point: 142.9 °C
• PSA: 67.43000
• Density: 1.29 g/cm³
• LogP: 2.47300
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Ethyl1,3-benzothiazole-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE

There total 7 articles about ETHYL 1,3-BENZOTHIAZOLE-2-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-[2-(4-methoxybenzylsulfanyl)phenyl]oxalamic acid ethyl ester + thiourea (17356-08-0) + trifluoroacetic acid (76-05-1) → benzothiazole-2-carboxylic acid ethyl ester (32137-76-1) + C9H12N2OS*C2HF3O2

Guidance literature:

at 80 ℃; for 2h; Green chemistry;

DOI:10.1016/j.tetlet.2015.02.054

Reference yield: 95.0%

C18H19NO4S + thiourea (17356-08-0) + trifluoroacetic acid (76-05-1) → benzothiazole-2-carboxylic acid ethyl ester (32137-76-1) + C9H12N2OS*C2HF3O2

Guidance literature:

at 80 ℃; for 2h; Green chemistry;

DOI:10.1016/j.tetlet.2015.02.054

Reference yield: 95.0%

C20H23NO6S + thiourea (17356-08-0) + trifluoroacetic acid (76-05-1) → benzothiazole-2-carboxylic acid ethyl ester (32137-76-1) + C11H16N2O3S*C2HF3O2

Guidance literature:

at 80 ℃; for 2h; Green chemistry;

DOI:10.1016/j.tetlet.2015.02.054

upstream raw materials:

ethyl 2-ethoxy-2-iminoacetate

2-amino-benzenethiol

1,3-benzothiazole-2-carbohydrazide

ethanol

Downstream raw materials:

1,3-benzothiazole-2-carbohydrazide

N-Isopropyl-2-benzothiazolcarboxamid

benzothiazole-2-amide

3-(benzothiazol-2-yl)-3-oxo-propanenitrile