Benzene, 2-[3-chloro-3-methyl-2-(phenylthio)butyl]-1,4-dimethoxy-

Base Information

• Chemical Name: Benzene, 2-[3-chloro-3-methyl-2-(phenylthio)butyl]-1,4-dimethoxy-
• CAS No.: 94828-08-7
• Molecular Formula: C₁₉H₂₃ClO₂S
• Molecular Weight: 350.909
• Mol file: 94828-08-7.mol

Synonyms:Benzene,2-[3-chloro-3-methyl-2-(phenylthio)butyl]-1,4-dimethoxy;

Chemical Property of Benzene, 2-[3-chloro-3-methyl-2-(phenylthio)butyl]-1,4-dimethoxy-

Chemical Property:

• Boiling Point: 461.9±45.0 °C(Predicted)
• PSA: 43.76000
• Density: 1.15±0.1 g/cm3(Predicted)
• LogP: 5.42460

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 2-[3-chloro-3-methyl-2-(phenylthio)butyl]-1,4-dimethoxy-

There total 1 articles about Benzene, 2-[3-chloro-3-methyl-2-(phenylthio)butyl]-1,4-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(3-methyl-2-buten-1-yl)-1,4-dimethoxybenzene (79233-13-9) + benzenesulfenyl chloride (931-59-9) → 2-(3-Chloro-3-methyl-2-phenylsulfanyl-butyl)-1,4-dimethoxy-benzene (94828-08-7)

Guidance literature:

In dichloromethane; at -20 ℃; for 0.166667h;

DOI:10.1248/cpb.32.3952

Reference yield:

2-(3-Chloro-3-methyl-2-phenylsulfanyl-butyl)-1,4-dimethoxy-benzene (94828-08-7) → 2-(3'-methyl-2'-phenylthio-3'-butenyl)-1,4-dimethoxybenzene (94828-21-4)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 60 ℃; for 40h; Yield given;

DOI:10.1248/cpb.32.3952

Reference yield:

2-(3-Chloro-3-methyl-2-phenylsulfanyl-butyl)-1,4-dimethoxy-benzene (94828-08-7) → 2-(4'-hydroxy-3'-methyl-2'-(E)-butenyl)-1,4-dimethoxybenzene (94828-28-1)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / dimethylformamide / 40 h / 60 °C

2: 310 mg / 30percent H₂O₂ / acetic acid / 16 h / Ambient temperature

3: trimethyl phosphite / methanol / 48 h / Ambient temperature

With dihydrogen peroxide; triethylamine; phosphorous acid trimethyl ester; In methanol; acetic acid; N,N-dimethyl-formamide;

DOI:10.1248/cpb.32.3952

upstream raw materials:

5-(3-methyl-2-buten-1-yl)-1,4-dimethoxybenzene

benzenesulfenyl chloride

Downstream raw materials:

2-(3'-methyl-2'-phenylthio-3'-butenyl)-1,4-dimethoxybenzene

2-(4'-hydroxy-3'-methyl-2'-(E)-butenyl)-1,4-dimethoxybenzene