6-Hydrazinopurine

Base Information

• Chemical Name: 6-Hydrazinopurine
• CAS No.: 5404-86-4
• Molecular Formula: C5H6 N6
• Molecular Weight: 150.143
• Hs Code.: 2933990090
• NSC Number: 7354
• UNII: 4PX9EKA7KY
• DSSTox Substance ID: DTXSID90202374
• Nikkaji Number: J113.494I
• Wikidata: Q72482864
• ChEMBL ID: CHEMBL394752
• Mol file: 5404-86-4.mol

Synonyms:6-Hydrazinopurine;5404-86-4;6-hydrazinyl-9H-purine;6-Hydrazino-1H-purine;Purine, 6-hydrazino-;6-hydrazinyl-7H-purine;7H-purin-6-ylhydrazine;N-Aminoadenine;6H-Purin-6-one, 1,7-dihydro-, hydrazone;6-HYDRAZINYL-1H-PURINE;NSC 7354;6-hydrazino-purine;5537-67-7;4PX9EKA7KY;1,7-Dihydro-6H-purin-6-one hydrazone;6-hydrazino-7(9)H-purine;GNF-PF-1671;NSC-7354;MFCD00703067;(9H-Purin-6-yl)hydrazine;6-hydrazino-7H-purine;UNII-4PX9EKA7KY;9H-Purine, 6-hydrazino-;Oprea1_856967;CHEMBL394752;SCHEMBL1095418;AMY2387;DTXSID90202374;NSC7354;9H-PURINE, 6-HYDRAZINYL-;BBL028884;STL290565;1,7-dihydro-6h-purin-6-onehydrazone;AKOS000192656;AKOS005177414;AKOS025402051;AKOS028109023;AC-3553;6H-Purin-6-one,7-dihydro-, hydrazone;(E)-6-hydrazono-6,7-dihydro-1H-purine;DS-12693;LS-127093;CS-0155488;FT-0635674;EN300-51129;6-Hydrazinyl-9H-purine;D70741;A829926;Z295458316

Chemical Property of 6-Hydrazinopurine

Chemical Property:

• Appearance/Colour: White to light yellow crystalline powder
• Vapor Pressure: 0.000564mmHg at 25°C
• Melting Point: 150.14
• Boiling Point: 616.9 °C at 760 mmHg
• PKA: 10.06±0.20(Predicted)
• Flash Point: 326.9 °C
• PSA: 92.51000
• Density: 1.702 g/cm³
• LogP: 0.41180
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 150.06539422
• Heavy Atom Count: 11
• Complexity: 139

Purity/Quality:

98% ^*data from raw suppliers

6-Hydrazinopurine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=NC2=C(N1)C(=NC=N2)NN

Technology Process of 6-Hydrazinopurine

There total 12 articles about 6-Hydrazinopurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

6-chloropurine (87-42-3) → 6-hydrazinyl-7H-purine (5404-86-4)

Guidance literature:

With hydrazine hydrate; In ethanol; for 2h; Heating;

DOI:10.1002/chem.200600282

Reference yield: 93.0%

6-bromopurine (767-69-1) → 6-hydrazinyl-7H-purine (5404-86-4)

Guidance literature:

With hydrazine hydrate; In ethanol; for 0.5h; Heating;

DOI:10.1002/chem.200600282

Reference yield: 82.0%

6-Mercaptopurine (157930-09-1,157930-10-4,157930-11-5,157930-13-7,157930-14-8) → 6-hydrazinyl-7H-purine (5404-86-4)

Guidance literature:

With hydrazine hydrate; for 30h; Heating;

DOI:10.1002/jhet.2969

upstream raw materials:

6-chloro-7H-purine

6-(methylthio)-1H-purine

6H-purine-6-thione

1,7-dihydro-6H-purin-6-one

Downstream raw materials:

9H-1,2,4-Triazolo[3,4-i]purine

purine

(E)-6-(2-(3-iodobenzylidene)hydrazinyl)-9H-purine

2-chloro-6-fluoro-N'-(9H-purin-6-yl)benzohydrazide