1-(4-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane

Base Information

Chemical Name:1-(4-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane
CAS No.:64169-45-5
Molecular Formula:C19H21 Cl F N O
Molecular Weight:333.833
Hs Code.:
UNII:69X04IVZ4W
Nikkaji Number:J981.613E
Wikidata:Q27264389
Mol file:64169-45-5.mol

Synonyms:64169-45-5;1-(4-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane;LU 10-134C;UNII-69X04IVZ4W;69X04IVZ4W;3-(5-Chloro-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl)-N,N-dimethylpropan-1-amine;3-[5-chloro-1-(4-fluorophenyl)-3H-2-benzofuran-1-yl]-N,N-dimethylpropan-1-amine;Citalopram hydrobromide impurity E [EP];Citalopram hydrochloride impurity E [EP];(+/-)-1-(4-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane;1-Isobenzofuranpropanamine, 5-chloro-1-(4-fluorophenyl)-1,3-dihydro-N,N-dimethyl-;3-((1RS)-5-Chloro-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl)-N,N-dimethylpropan-1-amine;5-chloro-1-(3-diMethylaMinopropyl)-1-(4-fluorophenyl)-phthalan;SCHEMBL141871;Q27264389;CITALOPRAM HYDROBROMIDE IMPURITY E [EP IMPURITY];CITALOPRAM HYDROCHLORIDE IMPURITY E [EP IMPURITY];{3-[5-chloro-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]propyl}dimethylamine;5-Chloro-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran

Suppliers and Price of 1-(4-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(4-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane

Chemical Property:

PSA：12.47000
LogP:4.59470
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:333.1295701
Heavy Atom Count:23
Complexity:386

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCC1(C2=C(CO1)C=C(C=C2)Cl)C3=CC=C(C=C3)F

Technology Process of 1-(4-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane

There total 1 articles about 1-(4-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64169-45-5
Lu 10-134-C

Guidance literature:: 5-Chlorphthalid, 1) 4-Fluorphenylmagnesiumbromid, 2) (CH3)2N-CH2-CH2-CH2-MgCl, 3) H3PO4;

Reference yield:

: 773837-37-9
sodium cyanide

: 64169-45-5
Lu 10-134-C

: 59729-33-8
1-(3-dimethylamino-propyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile

Guidance literature:: Lu 10-134-C; With triphenylphosphine; nickel dichloride; zinc; In acetonitrile; for 1.16667h; Heating / reflux;

sodium cyanide; In acetonitrile; at 20 ℃; for 15h; Heating / reflux;