BUTTPARK 153\57-10

Base Information

• Chemical Name: BUTTPARK 153\57-10
• CAS No.: 95104-43-1
• Molecular Formula: C₉H₁₃NO₄
• Molecular Weight: 199.207
• Hs Code.: 2934999090
• Mol file: 95104-43-1.mol

Synonyms:

Chemical Property of BUTTPARK 153\57-10

Chemical Property:

• PSA: 72.56000
• LogP: 1.21300

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 5-(1-hydroxyethyl)-3-methylsoxazole-4-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BUTTPARK 153\57-10

There total 3 articles about BUTTPARK 153\57-10 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

dimethyl-2,5 ethoxycarbonyl-4 <2H>-furannone-3 (39156-54-2) → 5-(1-Hydroxy-ethyl)-3-methyl-isoxazole-4-carboxylic acid ethyl ester (95104-43-1)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; for 1h; Heating;

DOI:10.1055/s-1984-31002

Reference yield:

ethyl 3-methylaminocrotonate (870-85-9) → 5-(1-Hydroxy-ethyl)-3-methyl-isoxazole-4-carboxylic acid ethyl ester (95104-43-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / diethyl ether / Ambient temperature

2: hydroxylamine hydrochloride, acetic acid / 0.5 h / Heating

With pyridine; hydroxylamine hydrochloride; acetic acid; In diethyl ether;

Reference yield:

4-Acetoxy-2-[1-methylamino-eth-(E)-ylidene]-3-oxo-pentanoic acid ethyl ester → 5-(1-Hydroxy-ethyl)-3-methyl-isoxazole-4-carboxylic acid ethyl ester (95104-43-1)

Guidance literature:

With hydroxylamine hydrochloride; acetic acid; for 0.5h; Yield given; Heating;

upstream raw materials:

dimethyl-2,5 ethoxycarbonyl-4 <2H>-furannone-3

ethyl 3-methylaminocrotonate

Downstream raw materials:

5-Benzyl-3,7-dimethyl-5H-isoxazolo[4,5-d]pyridazin-4-one

3,7-Dimethyl-5-phenyl-5H-isoxazolo[4,5-d]pyridazin-4-one

3,7-dimethyl[1,2]oxazolo[4,5-d]pyridazin-4(5H)-one

ethyl 5-acetyl-3-methylisoxazole-4-carboxylate