1,4-Dideoxy-1,4-imino-L-arabinitol HCl

Base Information

• Chemical Name: 1,4-Dideoxy-1,4-imino-L-arabinitol HCl
• CAS No.: 100991-91-1
• Molecular Formula: C₅H₁₁NO₃*ClH
• Molecular Weight: 169.608
• Mol file: 100991-91-1.mol

Synonyms:3,4-Pyrrolidinediol,2-(hydroxymethyl)-, hydrochloride, (2S,3S,4S)- (9CI); 3,4-Pyrrolidinediol,2-(hydroxymethyl)-, hydrochloride, [2S-(2a,3b,4a)]-

Chemical Property of 1,4-Dideoxy-1,4-imino-L-arabinitol HCl

Chemical Property:

• Boiling Point: 319.1°Cat760mmHg
• Flash Point: 188.8°C
• PSA: 72.72000
• Density: 1.368g/cm³
• LogP: -1.19690

Purity/Quality:

(2S,3S,4S)-2-(HYDROXYMETHYL)PYRROLIDINE-3,4-DIOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4-Dideoxy-1,4-imino-L-arabinitol HCl

There total 16 articles about 1,4-Dideoxy-1,4-imino-L-arabinitol HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3,5-tri-O-benzyl-1,4-dideoxy-1,4-imino-N-benzyl-L-arabinitol (126264-87-7) → 1,4-dideoxy-1,4-imino-L-arabinitol hydrochloride (100991-91-1)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 24h; under 1500.1 Torr;

DOI:10.1080/00397919208020496

Reference yield: 100.0%

4-azido-4-deoxy-L-arabinopyranose → 1,4-dideoxy-1,4-imino-L-arabinitol hydrochloride (100991-91-1) + (3R,4S,5S)-5-Amino-2-methoxy-tetrahydro-pyran-3,4-diol (3964-11-2,13143-97-0,76822-39-4,138921-42-3,147384-49-4,147384-52-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In hydrogenchloride; for 6h; Ambient temperature;

DOI:10.1016/0008-6215(88)84118-1

Reference yield: 100.0%

1-benzyl-3,4-dihydroxy-2-hydroxymethylpyrrolidine hydrochloride (1577180-48-3) → 1,4-dideoxy-1,4-imino-L-arabinitol hydrochloride (100991-91-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In water; at 20 ℃;

DOI:10.1002/jhet.1634

upstream raw materials:

(2S,3S,4S)-2-(hydroxymethyl)pyrrolidine-3,4-diol

2,3,5-tri-O-benzyl-1,4-dideoxy-1,4-imino-N-benzyl-L-arabinitol

3,5(S)-O-benzylidene-1,4-dideoxy-1,4-imino-L-arabinitol

methyl 2,3-O-isopropylidene-β-D-xylopyranoside