Leucine, N-(phenylmethoxy)-, methyl ester

Base Information

• Chemical Name: Leucine, N-(phenylmethoxy)-, methyl ester
• CAS No.: 95205-01-9
• Molecular Formula: C₁₄H₂₁NO₃
• Molecular Weight: 251.326
• Mol file: 95205-01-9.mol

Synonyms:

Chemical Property of Leucine, N-(phenylmethoxy)-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Leucine, N-(phenylmethoxy)-, methyl ester

There total 6 articles about Leucine, N-(phenylmethoxy)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

Isobutyl iodide (513-38-2) + methyl 2-(benzyloxyimino)acetate (120104-68-9) → methyl 2-(benzyloxyamino)-4-methylpentanoate (95205-01-9) + methyl 2-(benzyloxyamino)butanoate (95205-00-8)

Guidance literature:

With triethyl borane; In hexane; dichloromethane; at 25 ℃;

Reference yield:

Isobutyl iodide (513-38-2) + (E)-[(phenylmethoxy)imino] acetic acid methyl ester (57451-13-5) → methyl 2-(benzyloxyamino)-4-methylpentanoate (95205-01-9)

Guidance literature:

With triethyl borane; tri-n-butyl-tin hydride; In hexane; dichloromethane; at 25 ℃; for 0.25h;

DOI:10.1016/S0040-4020(00)00119-8

Reference yield:

Isobutyl iodide (513-38-2) + methyl 2-(benzyloxyimino)acetate (120104-68-9) → methyl 2-(benzyloxyamino)-4-methylpentanoate (95205-01-9)

Guidance literature:

With triethyl borane; tri-n-butyl-tin hydride; In hexane; dichloromethane; at 25 ℃; for 0.25h; Yield given;

DOI:10.1039/a807017b

upstream raw materials:

diazomethane

2-(benzyloxyamino)-4-methylpentanoic acid

Isobutyl iodide

methyl 2-(benzyloxyimino)acetate