Benzene, 1,4-bis(bromomethyl)-2,5-dimethoxy-3,6-dimethyl-

Base Information

• Chemical Name: Benzene, 1,4-bis(bromomethyl)-2,5-dimethoxy-3,6-dimethyl-
• CAS No.: 95306-71-1
• Molecular Formula: C12H16Br2O2
• Molecular Weight: 352.066
• Mol file: 95306-71-1.mol

Synonyms:

Chemical Property of Benzene, 1,4-bis(bromomethyl)-2,5-dimethoxy-3,6-dimethyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, 1,4-bis(bromomethyl)-2,5-dimethoxy-3,6-dimethyl-

There total 2 articles about Benzene, 1,4-bis(bromomethyl)-2,5-dimethoxy-3,6-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethylhydroquinone (615-90-7) → 1,4-di(bromomethyl)-2,5-dimethoxy-3,6-dimethylbenzene (95306-71-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / Reflux

2: hydrogen bromide; acetic acid / 72 h / 50 °C

With hydrogen bromide; potassium carbonate; acetic acid; In acetone;

DOI:10.1002/ejoc.201701124

Reference yield:

2,5-Dimethyl-1,4-benzoquinone (137-18-8) → 1,4-di(bromomethyl)-2,5-dimethoxy-3,6-dimethylbenzene (95306-71-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium dithionite / water; diethyl ether / 20 °C

2: potassium carbonate / acetone / Reflux

3: hydrogen bromide; acetic acid / 72 h / 50 °C

With sodium dithionite; hydrogen bromide; potassium carbonate; acetic acid; In diethyl ether; water; acetone;

DOI:10.1002/ejoc.201701124

Reference yield: 97.0%

1,4-di(bromomethyl)-2,5-dimethoxy-3,6-dimethylbenzene (95306-71-1) → 3,6-dimethoxy-2,5-dimethylterephtaldicarboxaldehyde (71804-46-1)

Guidance literature:

With dipotassium hydrogenphosphate; Potassium benzeneselenite; dibenzo-18-crown-6; In acetonitrile; for 30h;

DOI:10.1055/s-1984-30956

upstream raw materials:

2,5-dimethylhydroquinone

2,5-Dimethyl-1,4-benzoquinone

Downstream raw materials:

3,6-dimethoxy-2,5-dimethylterephtaldicarboxaldehyde