Methanone, (4-chlorophenyl)(3-hydroxy-4-(methylamino)phenyl)-

Base Information

Chemical Name:Methanone, (4-chlorophenyl)(3-hydroxy-4-(methylamino)phenyl)-
CAS No.:123172-46-3
Molecular Formula:C14H12 Cl N O2
Molecular Weight:261.7036
Hs Code.:
DSSTox Substance ID:DTXSID20153880
Wikidata:Q83020910
Mol file:123172-46-3.mol

Synonyms:BRN 5948117;Methanone, (4-chlorophenyl)(3-hydroxy-4-(methylamino)phenyl)-;(4-Chlorophenyl)(3-hydroxy-4-(methylamino)phenyl)methanone;123172-46-3;DTXSID20153880;LS-91172

Suppliers and Price of Methanone, (4-chlorophenyl)(3-hydroxy-4-(methylamino)phenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Methanone, (4-chlorophenyl)(3-hydroxy-4-(methylamino)phenyl)-

Chemical Property:

Vapor Pressure:8.44E-09mmHg at 25°C
Boiling Point:452.3°Cat760mmHg
Flash Point:227.4°C
Density:1.325g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:261.0556563
Heavy Atom Count:18
Complexity:290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=C(C=C(C=C1)C(=O)C2=CC=C(C=C2)Cl)O

Technology Process of Methanone, (4-chlorophenyl)(3-hydroxy-4-(methylamino)phenyl)-

There total 3 articles about Methanone, (4-chlorophenyl)(3-hydroxy-4-(methylamino)phenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 123172-44-1
6-(4-Chloro-benzoyl)-3-methyl-3H-benzooxazol-2-one

: 123172-46-3
(4-Chloro-phenyl)-(3-hydroxy-4-methylamino-phenyl)-methanone

Guidance literature:: With sodium hydroxide;
DOI:10.1016/0223-5234(89)90164-5

Reference yield:

: 21892-80-8
3-methylbenzo[d]oxazol-2(3H)-one

: 123172-46-3
(4-Chloro-phenyl)-(3-hydroxy-4-methylamino-phenyl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / polyphosphoric acid / 4.5 h / 120 °C

2: 85 percent / NaOH

With sodium hydroxide; PPA;
DOI:10.1016/0223-5234(89)90164-5

Reference yield:

: 74-11-3
para-chlorobenzoic acid

: 123172-46-3
(4-Chloro-phenyl)-(3-hydroxy-4-methylamino-phenyl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / polyphosphoric acid / 4.5 h / 120 °C

2: 85 percent / NaOH

With sodium hydroxide; PPA;
DOI:10.1016/0223-5234(89)90164-5