3-((4-(N-(((phenylsulfonyl)carbamoyl)phenylmethyl)-N-ethylamino)phenyl)methyl)-5,7-dimethyl-2-ethyl-3H-imidazo(4,5-b)pyridine

Base Information

Chemical Name:3-((4-(N-(((phenylsulfonyl)carbamoyl)phenylmethyl)-N-ethylamino)phenyl)methyl)-5,7-dimethyl-2-ethyl-3H-imidazo(4,5-b)pyridine
CAS No.:151954-37-9
Molecular Formula:C₃₃H₃₅N₅O₃S
Molecular Weight:581.739
Hs Code.:
Mol file:151954-37-9.mol

Synonyms:Benzeneacetamide,a-[ethyl[4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]phenyl]amino]-N-(phenylsulfonyl)-,(?à)-; 3H-Imidazo[4,5-b]pyridine,benzeneacetamide deriv.

Suppliers and Price of 3-((4-(N-(((phenylsulfonyl)carbamoyl)phenylmethyl)-N-ethylamino)phenyl)methyl)-5,7-dimethyl-2-ethyl-3H-imidazo(4,5-b)pyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-((4-(N-(((phenylsulfonyl)carbamoyl)phenylmethyl)-N-ethylamino)phenyl)methyl)-5,7-dimethyl-2-ethyl-3H-imidazo(4,5-b)pyridine

Chemical Property:

Boiling Point:°Cat760mmHg
PKA:4.92±0.10(Predicted)
Flash Point:°C
Density:1.23g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-((4-(N-(((phenylsulfonyl)carbamoyl)phenylmethyl)-N-ethylamino)phenyl)methyl)-5,7-dimethyl-2-ethyl-3H-imidazo(4,5-b)pyridine

There total 8 articles about 3-((4-(N-(((phenylsulfonyl)carbamoyl)phenylmethyl)-N-ethylamino)phenyl)methyl)-5,7-dimethyl-2-ethyl-3H-imidazo(4,5-b)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133240-06-9
5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridine

: 151954-37-9
3-<<4-phenyl>methyl>-5,7-dimethyl-2-ethyl-3H-imidazo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, 2 h

2: 85 percent / H₂ / 5percent Pd/C / methanol / 2 h / 2068.6 Torr

3: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, 18 h

4: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, overnight

5: 92 percent / 1N aq. LiOH / methanol

6: 1.) 1,1'-carbonyldiimidazole, 2.) 1,8-diazabicyclo<5.4.0>undec-7-ene / 1.) THF, 18 h, 2.) THF, reflux, 24 h

With lithium hydroxide; hydrogen; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,1'-carbonyldiimidazole; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00078a014

Reference yield:

: 137421-60-4
3-[(4-nitrophenyl)methyl]-5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridine

: 151954-37-9
3-<<4-phenyl>methyl>-5,7-dimethyl-2-ethyl-3H-imidazo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / H₂ / 5percent Pd/C / methanol / 2 h / 2068.6 Torr

2: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, 18 h

3: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, overnight

4: 92 percent / 1N aq. LiOH / methanol

5: 1.) 1,1'-carbonyldiimidazole, 2.) 1,8-diazabicyclo<5.4.0>undec-7-ene / 1.) THF, 18 h, 2.) THF, reflux, 24 h

With lithium hydroxide; hydrogen; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,1'-carbonyldiimidazole; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00078a014

Reference yield:

: 100-11-8
1-bromomethyl-4-nitro-benzene

: 151954-37-9
3-<<4-phenyl>methyl>-5,7-dimethyl-2-ethyl-3H-imidazo<4,5-b>pyridine

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, 2 h

2: 85 percent / H₂ / 5percent Pd/C / methanol / 2 h / 2068.6 Torr

3: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, 18 h

4: 1.) NaH / 1.) DMF, 5 min, 2.) DMF, overnight

5: 92 percent / 1N aq. LiOH / methanol

6: 1.) 1,1'-carbonyldiimidazole, 2.) 1,8-diazabicyclo<5.4.0>undec-7-ene / 1.) THF, 18 h, 2.) THF, reflux, 24 h

With lithium hydroxide; hydrogen; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,1'-carbonyldiimidazole; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00078a014